Andrea Coluccio
Overview
Explore the profile of Andrea Coluccio including associated specialties, affiliations and a list of published articles.
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13
Citations
911
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0
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Recent Articles
1.
Stojanovic Guzvic N, Luke F, Treitschke S, Coluccio A, Hoffmann M, Feliciello G, et al.
Mol Oncol
. 2024 Oct;
PMID: 39367702
While cell-free liquid biopsy (cfLB) approaches provide simple and inexpensive disease monitoring, cell-based liquid biopsy (cLB) may enable additional molecular genetic assessment of systemic disease heterogeneity and preclinical model development....
2.
Giansanti P, Samaras P, Bian Y, Meng C, Coluccio A, Frejno M, et al.
Nat Methods
. 2022 Jun;
19(7):803-811.
PMID: 35710609
The laboratory mouse ranks among the most important experimental systems for biomedical research and molecular reference maps of such models are essential informational tools. Here, we present a quantitative draft...
3.
Falcomata C, Barthel S, Widholz S, Schneeweis C, Montero J, Toska A, et al.
Nat Cancer
. 2022 Feb;
3(3):318-336.
PMID: 35122074
KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) is highly immunosuppressive and resistant to targeted and immunotherapies. Among the different PDAC subtypes, basal-like mesenchymal PDAC, which is driven by allelic imbalance, increased gene...
4.
Scheiter A, Evert K, Reibenspies L, Cigliano A, Annweiler K, Muller K, et al.
Mol Oncol
. 2021 Nov;
16(5):1091-1118.
PMID: 34748271
Aberrant activation of the phosphoinositide 3-kinase (PI3K)/AKT/mTOR and Ras/mitogen-activated protein kinase (MAPK) pathways is a hallmark of hepatocarcinogenesis. In a subset of hepatocellular carcinomas (HCCs), PI3K/AKT/mTOR signaling dysregulation depends on...
5.
Biederstadt A, Hassan Z, Schneeweis C, Schick M, Schneider L, Muckenhuber A, et al.
Gut
. 2020 Feb;
69(8):1472-1482.
PMID: 32001555
Objective: Pancreatic ductal adenocarcinoma (PDAC) still carries a dismal prognosis with an overall 5-year survival rate of 9%. Conventional combination chemotherapies are a clear advance in the treatment of PDAC;...
6.
Helleboid P, Heusel M, Duc J, Piot C, Thorball C, Coluccio A, et al.
EMBO J
. 2019 Aug;
38(18):e101220.
PMID: 31403225
Krüppel-associated box (KRAB)-containing zinc finger proteins (KZFPs) are encoded in the hundreds by the genomes of higher vertebrates, and many act with the heterochromatin-inducing KAP1 as repressors of transposable elements...
7.
Takahashi N, Coluccio A, Thorball C, Planet E, Shi H, Offner S, et al.
Genes Dev
. 2019 Jan;
33(1-2):49-54.
PMID: 30602440
Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation, causing parental origin-specific monoallelic gene expression. Zinc finger protein 57 (ZFP57) is critical for maintenance of this epigenetic memory...
8.
Jang S, Kauzlaric A, Quivy J, Pontis J, Rauwel B, Coluccio A, et al.
Nucleic Acids Res
. 2018 Jun;
46(17):8788-8802.
PMID: 29955894
During cell division, maintenance of chromatin features from the parental genome requires their proper establishment on its newly synthetized copy. The loss of epigenetic marks within heterochromatin, typically enriched in...
9.
Coluccio A, Ecco G, Duc J, Offner S, Turelli P, Trono D
Epigenetics Chromatin
. 2018 Feb;
11(1):7.
PMID: 29482634
Background: The KZFP/KAP1 (KRAB zinc finger proteins/KRAB-associated protein 1) system plays a central role in repressing transposable elements (TEs) and maintaining parent-of-origin DNA methylation at imprinting control regions (ICRs) during...
10.
de Iaco A, Planet E, Coluccio A, Verp S, Duc J, Trono D
Nat Genet
. 2017 May;
49(6):941-945.
PMID: 28459456
In animal embryos, transcription is mostly silent for several cell divisions, until the release of the first major wave of embryonic transcripts through so-called zygotic genome activation (ZGA). Maternally provided...