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Andrea Cerquone Perpetuini

Explore the profile of Andrea Cerquone Perpetuini including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 279
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Recent Articles
1.
Vumbaca S, Giuliani G, Fiorentini V, Tortolici F, Cerquone Perpetuini A, Riccio F, et al.
Biomolecules . 2021 Aug; 11(8). PMID: 34439837
Repeated mechanical stress causes injuries in the adult skeletal muscle that need to be repaired. Although muscle regeneration is a highly efficient process, it fails in some pathological conditions, compromising...
2.
Reggio A, Rosina M, Palma A, Cerquone Perpetuini A, Petrilli L, Gargioli C, et al.
Cell Death Differ . 2020 May; 27(10):2921-2941. PMID: 32382110
Fibro/Adipogenic Progenitors (FAPs) are muscle-interstitial progenitors mediating pro-myogenic signals that are critical for muscle homeostasis and regeneration. In myopathies, the autocrine/paracrine constraints controlling FAP adipogenesis are released causing fat infiltrates....
3.
Cerquone Perpetuini A, Giuliani G, Reggio A, Cerretani M, Santoriello M, Stefanelli R, et al.
Sci Rep . 2020 Mar; 10(1):5363. PMID: 32210313
Muscle resident fibro-adipogenic progenitors (FAPs), support muscle regeneration by releasing cytokines that stimulate the differentiation of myogenic stem cells. However, in non-physiological contexts (myopathies, atrophy, aging) FAPs cause fibrotic and...
4.
Sundaramurthi H, Moran A, Cerquone Perpetuini A, Reynolds A, Kennedy B
Adv Exp Med Biol . 2019 Dec; 1185:263-267. PMID: 31884622
Worldwide, 1 in 2000 people suffer from inherited retinal dystrophies (IRD). Individuals with IRD typically present with progressive vision loss that ultimately results in blindness. Unfortunately, effective treatment options are...
5.
Palma A, Cerquone Perpetuini A, Ferrentino F, Fuoco C, Gargioli C, Giuliani G, et al.
Front Physiol . 2019 Oct; 10:1216. PMID: 31611808
Muscle regeneration is a complex process governed by the interplay between several muscle-resident mononuclear cell populations. Following acute or chronic damage these cell populations are activated, communicate via cell-cell interactions...
6.
Marinkovic M, Fuoco C, Sacco F, Cerquone Perpetuini A, Giuliani G, Micarelli E, et al.
Life Sci Alliance . 2019 Jun; 2(3). PMID: 31239312
Fibro-adipogenic progenitors (FAPs) promote satellite cell differentiation in adult skeletal muscle regeneration. However, in pathological conditions, FAPs are responsible for fibrosis and fatty infiltrations. Here we show that the NOTCH...
7.
Cerquone Perpetuini A, Mathoux J, Kennedy B
Neural Regen Res . 2018 Dec; 14(1):85-86. PMID: 30531081
No abstract available.
8.
Cerquone Perpetuini A, Re Cecconi A, Chiappa M, Martinelli G, Fuoco C, Desiderio G, et al.
J Cachexia Sarcopenia Muscle . 2018 May; 9(4):727-746. PMID: 29781585
Background: Skeletal muscle is characterized by an efficient regeneration potential that is often impaired during myopathies. Understanding the molecular players involved in muscle homeostasis and regeneration could help to find...
9.
Perfetto L, Briganti L, Calderone A, Cerquone Perpetuini A, Iannuccelli M, Langone F, et al.
Nucleic Acids Res . 2015 Oct; 44(D1):D548-54. PMID: 26467481
Assembly of large biochemical networks can be achieved by confronting new cell-specific experimental data with an interaction subspace constrained by prior literature evidence. The SIGnaling Network Open Resource, SIGNOR (available...