Andrea Bahr
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Explore the profile of Andrea Bahr including associated specialties, affiliations and a list of published articles.
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52
Citations
821
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Recent Articles
1.
Jaudas F, Bartenschlager F, Shashikadze B, Santamaria G, Reichart D, Schnell A, et al.
Sci Transl Med
. 2025 Jan;
17(782):eadk9145.
PMID: 39841805
In patients with cystic fibrosis (CF), repeated cycles of infection and inflammation eventually lead to fatal lung damage. Although diminished mucus clearance can be restored by highly effective CFTR modulator...
2.
Seitz I, Peters T, Reichel F, Bahr A, Auch H, Motlik J, et al.
Invest Ophthalmol Vis Sci
. 2024 Oct;
65(12):41.
PMID: 39466231
Purpose: Subretinal (SR) injection in porcine models is a promising avenue for preclinical evaluation of cell and gene therapies. Targeting of the subretinal fluid compartment (bleb) is critical to the...
3.
Bender M, Panelli A, Reichart B, Radan J, Mokelke M, Neumann E, et al.
Xenotransplantation
. 2024 Jun;
31(1):e12841.
PMID: 38864375
Introduction: Orthotopic cardiac xenotransplantation has seen notable improvement, leading to the first compassionate use in 2022. However, it remains challenging to define the clinical application of cardiac xenotransplantation, including the...
4.
Langin M, Buttgereit I, Reichart B, Panelli A, Radan J, Mokelke M, et al.
Transplantation
. 2023 Aug;
107(12):e328-e338.
PMID: 37643028
Background: Orthotopic cardiac xenotransplantation has seen substantial advancement in the last years and the initiation of a clinical pilot study is close. However, donor organ overgrowth has been a major...
5.
Stirm M, Shashikadze B, Blutke A, Kemter E, Lange A, Stockl J, et al.
Proc Natl Acad Sci U S A
. 2023 Jul;
120(29):e2301250120.
PMID: 37428903
Duchenne muscular dystrophy (DMD) is a fatal X-linked disease caused by mutations in the gene, leading to complete absence of dystrophin and progressive degeneration of skeletal musculature and myocardium. In...
6.
von Bibra C, Shibamiya A, Bahr A, Geertz B, Kohne M, Stuedemann T, et al.
Dis Model Mech
. 2023 Jun;
16(5).
PMID: 37272385
Engineered heart tissue (EHT) transplantation represents an innovative, regenerative approach for heart failure patients. Late preclinical trials are underway, and a first clinical trial started recently. Preceding studies revealed functional...
7.
Rawat H, Kornherr J, Zawada D, Bakhshiyeva S, Kupatt C, Laugwitz K, et al.
Front Cell Dev Biol
. 2023 Jun;
11:1111684.
PMID: 37261075
Domestic pigs () share many genetic, anatomical, and physiological traits with humans and therefore constitute an excellent preclinical animal model. Fundamental understanding of the cellular and molecular processes governing early...
8.
Rodriguez-Pineiro A, Jaudas F, Klymiuk N, Bahr A, Hansson G, Ermund A
Respir Res
. 2023 Mar;
24(1):83.
PMID: 36927357
Background: The respiratory tract is protected from inhaled particles and microbes by mucociliary clearance, mediated by the mucus and the cilia creating a flow to move the mucus cephalad. Submucosal...
9.
Kupatt C, Ziegler T, Bahr A, le Noble F
Int Immunopharmacol
. 2023 Feb;
117:109786.
PMID: 36812671
Since clinical revascularization techniques of coronary or peripheral artery disease (CAD/PAD) focus on macrovessels of the heart, the microcirculatory compartment largely goes unnoticed. However, cardiovascular risk factors not only drive...
10.
Poch C, Foo K, De Angelis M, Jennbacken K, Santamaria G, Bahr A, et al.
Nat Cell Biol
. 2022 May;
24(5):659-671.
PMID: 35550611
Heart regeneration is an unmet clinical need, hampered by limited renewal of adult cardiomyocytes and fibrotic scarring. Pluripotent stem cell-based strategies are emerging, but unravelling cellular dynamics of host-graft crosstalk...