Andre G Tempone
Overview
Explore the profile of Andre G Tempone including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
93
Citations
573
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
21.
Romanelli M, Amaral M, Thevenard F, Santa Cruz L, Regasini L, Migotto A, et al.
ACS Omega
. 2022 Aug;
7(32):28561-28570.
PMID: 35990437
Chagas disease, caused by , affects seven million people worldwide and lacks effective treatments. Using bioactivity-guided fractionation, NMR, and electrospray ionization-high resolution mass spectrometry (ESI-HRMS) spectral analysis, the indole alkaloid...
22.
Maiolini T, Rosa W, Miranda D, Costa-Silva T, Tempone A, Bueno P, et al.
Chem Biodivers
. 2022 Apr;
19(6):e202200198.
PMID: 35485995
Chagas Disease (CD), caused by flagellate protozoan Trypanosoma cruzi, is a Neglected Tropical Diseases (NTD) that affect approximately seven million people worldwide with a restrict therapeutical arsenal. In the present...
23.
Freire V, Gubiani J, Spencer T, Hajdu E, Ferreira A, Ferreira D, et al.
J Nat Prod
. 2022 Apr;
85(5):1340-1350.
PMID: 35427139
Investigation of the marine sponge MeOH fractions using feature-based molecular networking, dereplication, and isolation led to the discovery of new bromopyrrole-derived metabolites. An in-house library of bromopyrrole alkaloids previously isolated...
24.
Dos Santos A, Amaral M, Hasegawa F, Lago J, Tempone A, Sartorelli P
Front Pharmacol
. 2022 Apr;
13:865432.
PMID: 35370638
[This corrects the article DOI: 10.3389/fphar.2021.734127.].
25.
Brito I, Thevenard F, Costa-Silva T, Oliveira S, Cunha R, de Oliveira E, et al.
Molecules
. 2022 Feb;
27(3).
PMID: 35164158
As part of our continuous studies involving the prospection of natural products from Brazilian flora aiming at the discovery of prototypes for the development of new antiparasitic drugs, the present...
26.
Varela M, Amaral M, Romanelli M, de Castro Levatti E, Tempone A, Fernandes J
Eur J Pharm Sci
. 2022 Jan;
171:106114.
PMID: 34986415
Trypanosoma cruzi is the causing agent of Chagas disease, a parasitic infection without efficient treatment for chronic patients. Despite the efforts, no new drugs have been approved for this disease...
27.
Tempone A, Pieper P, Borborema S, Thevenard F, Lago J, Croft S, et al.
Nat Prod Rep
. 2021 Dec;
38(12):2214-2235.
PMID: 34913053
Covering: 2000 up to 2021Natural products are an important resource in drug discovery, directly or indirectly delivering numerous small molecules for potential development as human medicines. Among the many classes...
28.
Dos Santos A, Amaral M, Hasegawa F, Lago J, Tempone A, Sartorelli P
Front Pharmacol
. 2021 Nov;
12:734127.
PMID: 34803682
Chagas disease is caused by the protozoan parasite and affects 6-8 million people worldwide, mainly from developing countries. The treatment is limited to two approved nitro-derivatives, nifurtimox and benznidazole, with...
29.
da Costa-Silva T, Silva M, Antar G, Tempone A, Lago J
Phytomedicine
. 2021 Oct;
93:153748.
PMID: 34628240
Background: In the present work the bioactivity-guided fractionation of n-hexane extract from aerial parts of Baccharis sphenophylla (Asteraceae) against trypomastigote forms of Trypanosoma cruzi was performed. Purpose: To evaluate the...
30.
Conserva G, Costa-Silva T, Quiros-Guerrero L, Marcourt L, Wolfender J, Queiroz E, et al.
Chem Biol Interact
. 2021 Sep;
349:109661.
PMID: 34537181
Phytochemical analysis of EtOH extract from leaves of Nectandra oppositifolia afforded three flavonoids: kaempferol (1), kaempferol-3-O-α-rhamnopyranoside (2) and kaempferol-3-O-α-(3,4-di-E-p-coumaroyl)-rhamnopyranoside (3), which were characterized by NMR and ESI-HRMS. When tested against...