Andre Bensadoun
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Explore the profile of Andre Bensadoun including associated specialties, affiliations and a list of published articles.
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58
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Recent Articles
11.
Bensadoun A, Mottler C, Pelletier C, Wu D, Seo J, Leung C, et al.
Biochim Biophys Acta
. 2014 Apr;
1841(7):970-6.
PMID: 24681165
Lipoprotein lipase (LPL) has been highly conserved through vertebrate evolution, making it challenging to generate useful antibodies. Some polyclonal antibodies against LPL have turned out to be nonspecific, and the...
12.
Robciuc M, Maranghi M, Lahikainen A, Rader D, Bensadoun A, Oorni K, et al.
Arterioscler Thromb Vasc Biol
. 2013 May;
33(7):1706-13.
PMID: 23661675
Objective: Angiopoietin-like 3 (Angptl3) is a regulator of lipoprotein metabolism at least by inhibiting lipoprotein lipase activity. Loss-of-function mutations in ANGPTL3 cause familial combined hypolipidemia through an unknown mechanism. Approach...
13.
Nyren R, Chang C, Lindstrom P, Barmina A, Vorrsjo E, Ali Y, et al.
BMC Physiol
. 2012 Nov;
12:14.
PMID: 23186339
Background: Lipoprotein lipase (LPL) hydrolyzes triglycerides in plasma lipoproteins and enables uptake of lipolysis products for energy production or storage in tissues. Our aim was to study the localization of...
14.
Davies B, Goulbourne C, Barnes 2nd R, Turlo K, Gin P, Vaughan S, et al.
J Lipid Res
. 2012 Sep;
53(12):2690-7.
PMID: 23008484
Lipoprotein lipase (LPL) is secreted into the interstitial spaces by adipocytes and myocytes but then must be transported to the capillary lumen by GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial...
15.
Gin P, Goulbourne C, Adeyo O, Beigneux A, Davies B, Tat S, et al.
Hum Mol Genet
. 2012 Apr;
21(13):2961-72.
PMID: 22493000
Lipoprotein lipase (LPL) is a 448-amino-acid head-to-tail dimeric enzyme that hydrolyzes triglycerides within capillaries. LPL is secreted by parenchymal cells into the interstitial spaces; it then binds to GPIHBP1 (glycosylphosphatidylinositol-anchored...
16.
Hosseini M, Ehrhardt N, Weissglas-Volkov D, Lai C, Mao H, Liao J, et al.
Arterioscler Thromb Vasc Biol
. 2012 Feb;
32(5):1204-10.
PMID: 22345169
Objective: Lipoprotein lipase (LPL) is a principal enzyme in lipoprotein metabolism, tissue lipid utilization, and energy metabolism. LPL is synthesized by parenchymal cells in adipose, heart, and muscle tissues followed...
17.
Bensadoun A, Nesheim M, Ross A
J Nutr
. 2011 Dec;
142(2):211-2.
PMID: 22190033
No abstract available.
18.
Rios J, Shastry S, Jasso J, Hauser N, Garg A, Bensadoun A, et al.
J Inherit Metab Dis
. 2011 Oct;
35(3):531-40.
PMID: 22008945
Lipoprotein lipase (LPL) is a hydrolase that cleaves circulating triglycerides to release fatty acids to the surrounding tissues. The enzyme is synthesized in parenchymal cells and is transported to its...
19.
Young S, Davies B, Voss C, Gin P, Weinstein M, Tontonoz P, et al.
J Lipid Res
. 2011 Aug;
52(11):1869-84.
PMID: 21844202
Interest in lipolysis and the metabolism of triglyceride-rich lipoproteins was recently reignited by the discovery of severe hypertriglyceridemia (chylomicronemia) in glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1)-deficient mice. GPIHBP1 is...
20.
Voss C, Davies B, Tat S, Gin P, Fong L, Pelletier C, et al.
Proc Natl Acad Sci U S A
. 2011 Apr;
108(19):7980-4.
PMID: 21518912
GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells, shuttles lipoprotein lipase (LPL) from subendothelial spaces to the capillary lumen. An absence of GPIHBP1 prevents the entry of LPL into capillaries,...