Andras Paldi
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Explore the profile of Andras Paldi including associated specialties, affiliations and a list of published articles.
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36
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918
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Recent Articles
1.
Kyratzi P, Matika O, Brassington A, Clare C, Xu J, Barrett D, et al.
Physiol Genomics
. 2024 Sep;
56(11):791-806.
PMID: 39250149
Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R. A. Fisher, genome-wide association studies (GWAS) extract information...
2.
Racine L, Parmentier R, Niphadkar S, Chhun J, Martignoles J, Delhommeau F, et al.
Life Sci Alliance
. 2024 May;
7(8).
PMID: 38802246
A continuous supply of energy is an essential prerequisite for survival and represents the highest priority for the cell. We hypothesize that cell differentiation is a process of optimization of...
3.
Kyratzi P, Matika O, Brassington A, Clare C, Xu J, Barrett D, et al.
bioRxiv
. 2024 Apr;
PMID: 38659791
Identifying associations between phenotype and genotype is the fundamental basis of genetic analyses. Inspired by frequentist probability and the work of R.A. Fisher, genome-wide association studies (GWAS) extract information using...
4.
Fourneaux C, Racine L, Koering C, Dussurgey S, Vallin E, Moussy A, et al.
BMC Biol
. 2024 Mar;
22(1):58.
PMID: 38468285
Background: Cell differentiation requires the integration of two opposite processes, a stabilizing cellular memory, especially at the transcriptional scale, and a burst of gene expression variability which follows the differentiation...
5.
Racine L, Paldi A
Methods Mol Biol
. 2023 Dec;
2745:163-176.
PMID: 38060185
The cells of a multicellular organism are derived from a single zygote and genetically almost identical. Yet, they are phenotypically very different. This difference is the result of a process...
6.
Gao N, Gandrillon O, Paldi A, Herbach U, Gunawan R
F1000Res
. 2023 Aug;
12:426.
PMID: 37545651
Single-cell studies have demonstrated the presence of significant cell-to-cell heterogeneity in gene expression. Whether such heterogeneity is only a bystander or has a functional role in the cell differentiation process...
7.
Aslan Kamil M, Fourneaux C, Yilmaz A, Stavros S, Parmentier R, Paldi A, et al.
PLoS One
. 2023 Aug;
18(8):e0288655.
PMID: 37527253
Cell lineage tracking is a long-standing and unresolved problem in biology. Microfluidic technologies have the potential to address this problem, by virtue of their ability to manipulate and process single-cells...
8.
Parmentier R, Racine L, Moussy A, Chantalat S, Sudharshan R, Gao N, et al.
PLoS Biol
. 2022 Oct;
20(10):e3001849.
PMID: 36288293
When human cord blood-derived CD34+ cells are induced to differentiate, they undergo rapid and dynamic morphological and molecular transformations that are critical for fate commitment. In particular, the cells pass...
9.
Moussy A, Gao N, Corre G, Poletti V, Majdoul S, Fenard D, et al.
Hum Gene Ther
. 2019 Apr;
30(8):1023-1034.
PMID: 30977420
The initial stages following the cytokine stimulation of human cord blood CD34+ cells overlap with the period when lentiviral gene transfer is typically performed. Single-cell transcriptional profiling and time-lapse microscopy...
10.
Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, et al.
Clin Pharmacol Ther
. 2018 Dec;
105(6):1477-1491.
PMID: 30506689
The cytochrome P450 (CYP)4F2 gene is known to influence mean coumarin dose. The aim of the present study was to undertake a meta-analysis at the individual patients level to capture...