Andras Kapus
Overview
Explore the profile of Andras Kapus including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
4378
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Recent Articles
11.
Ailenberg M, Kapus A, Ho Leung C, Szaszi K, Williams P, diCiano-Oliveira C, et al.
Shock
. 2022 Jun;
58(1):78-89.
PMID: 35670454
Resuscitation of trauma patients after hemorrhagic shock causes global I/R, which may contribute to organ dysfunction. Oxidative stress resulting from I/R is known to induce signaling pathways leading to the...
12.
Wang A, Coelho N, Arora P, Wang Y, Eymael D, Ji C, et al.
J Cell Physiol
. 2022 Feb;
237(5):2451-2468.
PMID: 35150133
Tissue fibrosis manifests as excessive deposition of compacted, highly aligned collagen fibrils, which interfere with organ structure and function. Cells in collagen-rich lesions often exhibit marked overexpression of discoidin domain...
13.
Ailenberg M, Kapus A, Rotstein O
Biotechniques
. 2021 Sep;
71(6):587-597.
PMID: 34519222
A new approach for improved RT-PCR is described. It is based on primers designed to form controlled stem-loop and homodimer configurations, hence the name 'double-bubble' primers. The primers contain three...
14.
Speight P, Rozycki M, Venugopal S, Szaszi K, Kofler M, Kapus A
iScience
. 2021 Jul;
24(7):102739.
PMID: 34278253
Turnover of the primary cilium (PC) is critical for proliferation and tissue homeostasis. Each key component of the PC resorption machinery, the HEF1/Aurora kinase A (AurA)/HDAC6 pathway harbors cis-elements potentially...
15.
Miranda M, Lichner Z, Szaszi K, Kapus A
Int J Mol Sci
. 2021 Jul;
22(11).
PMID: 34204945
A lesser known but crucially important downstream effect of Rho family GTPases is the regulation of gene expression. This major role is mediated via the cytoskeleton, the organization of which...
16.
Kofler M, Kapus A
Methods Mol Biol
. 2021 May;
2299:197-216.
PMID: 34028745
Myocardin-related transcription factor (MRTF) and the paralogous Hippo pathway effectors Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are transcriptional co-activators that play pivotal roles in myofibroblast generation...
17.
Godbout E, Son D, Hume S, Boo S, Sarrazy V, Clement S, et al.
Cells
. 2020 Dec;
9(12).
PMID: 33348602
We identify the focal adhesion protein kindlin-2 as player in a novel mechanotransduction pathway that controls profibrotic cardiac fibroblast to myofibroblast activation. Kindlin-2 is co-upregulated with the myofibroblast marker α-smooth...
18.
Yeung T, Fung O, Bashkurov M, Khandani A, Subedar O, Wudwud A, et al.
Oncotarget
. 2019 Dec;
10(62):6691-6712.
PMID: 31803363
The alkylating agent platinum is first-line chemotherapy treatment for high-grade serous carcinomas (HGSC) of tubal-ovarian origin. Platinum compounds cause DNA damage and induce apoptotic cell death in the bulk tumor...
19.
Dan Q, Shi Y, Rabani R, Venugopal S, Xiao J, Anwer S, et al.
J Biol Chem
. 2019 Sep;
294(42):15446-15465.
PMID: 31481470
The tight junctional pore-forming protein claudin-2 (CLDN-2) mediates paracellular Na and water transport in leaky epithelia and alters cancer cell proliferation. Previously, we reported that tumor necrosis factor-α time-dependently alters...
20.
Demian W, Persaud A, Jiang C, Coyaud E, Liu S, Kapus A, et al.
Cell Rep
. 2019 May;
27(6):1886-1896.e6.
PMID: 31067471
mTORC1 regulates cellular growth and is activated by growth factors and by essential amino acids such as Leu. Leu enters cells via the Leu transporter LAT1-4F2hc (LAT1). Here we show...