Andras Franko
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Explore the profile of Andras Franko including associated specialties, affiliations and a list of published articles.
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24
Citations
454
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Recent Articles
1.
Wissmiller K, Bilekova S, Franko A, Lutz S, Katsburg M, Gulde S, et al.
Mol Metab
. 2023 Mar;
71:101706.
PMID: 36931467
Objective: The insulin/insulin-like growth factor 1 (IGF1) pathway is emerging as a crucial component of prostate cancer progression. Therefore, we investigated the role of the novel insulin/IGF1 signaling modulator inceptor...
2.
Lutz S, Hennenlotter J, Franko A, Dannecker C, Fritsche L, Kantartzis K, et al.
J Clin Med
. 2022 Nov;
11(22).
PMID: 36431238
Although epidemiological studies suggest a lower prostate cancer incidence rate in patients with type 2 diabetes, cancer survival is markedly reduced. Underlying mechanisms that connect the two diseases are still...
3.
Franko A, Irmler M, Prehn C, Heinzmann S, Schmitt-Kopplin P, Adamski J, et al.
Biomedicines
. 2022 Mar;
10(3).
PMID: 35327418
Glucotoxic metabolites and pathways play a crucial role in diabetic complications, and new treatment options which improve glucotoxicity are highly warranted. In this study, we analyzed bezafibrate (BEZ) treated, streptozotocin...
4.
Franko A, Berti L, Hennenlotter J, Rausch S, Scharpf M, de Angelis M, et al.
Biomedicines
. 2020 Nov;
8(11).
PMID: 33207809
Type 2 diabetes (T2D) is associated with worse prognosis of prostate cancer (PCa). The molecular mechanisms behind this association are still not fully understood. The aim of this study was...
5.
Franko A, Berti L, Guirguis A, Hennenlotter J, Wagner R, Scharpf M, et al.
Genes (Basel)
. 2020 Oct;
11(10).
PMID: 33036464
Prostate cancer (PCa), the most incident cancer in men, is tightly regulated by endocrine signals. A number of different PCa cell lines are commonly used for in vitro experiments, but...
6.
Franko A, Berti L, Hennenlotter J, Rausch S, Scharpf M, de Angelis M, et al.
J Pers Med
. 2020 Sep;
10(3).
PMID: 32932589
Aldo-keto reductase family 1 (AKR1) enzymes play a crucial role in diabetic complications. Since type 2 diabetes (T2D) is associated with cancer progression, we investigated the impact of diabetes on...
7.
Bohm A, Keuper M, Meile T, Zdichavsky M, Fritsche A, Haring H, et al.
Sci Rep
. 2020 Jul;
10(1):12407.
PMID: 32709986
Among obese subjects, metabolically healthy (MHO) and unhealthy obese (MUHO) subjects exist, the latter being characterized by whole-body insulin resistance, hepatic steatosis, and subclinical inflammation. Insulin resistance and obesity are...
8.
Franko A, Shao Y, Heni M, Hennenlotter J, Hoene M, Hu C, et al.
Cancers (Basel)
. 2020 Jul;
12(7).
PMID: 32640711
Despite it being the most common incident of cancer among men, the pathophysiological mechanisms contributing to prostate cancer (PCa) are still poorly understood. Altered mitochondrial metabolism is postulated to play...
9.
Franko A, Hartwig S, Kotzka J, Ruoss M, Nussler A, Konigsrainer A, et al.
Nutrients
. 2019 Aug;
11(8).
PMID: 31382615
The liver plays a pivotal role in whole-body carbohydrate, lipid, and protein metabolism. One of the key regulators of glucose and lipid metabolism are hepatokines, which are found among the...
10.
Aatsinki S, Elkhwanky M, Kummu O, Karpale M, Buler M, Viitala P, et al.
Diabetes
. 2019 Mar;
68(5):918-931.
PMID: 30833469
Low 25-hydroxyvitamin D levels correlate with the prevalence of diabetes; however, the mechanisms remain uncertain. Here, we show that nutritional deprivation-responsive mechanisms regulate vitamin D metabolism. Both fasting and diabetes...