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Anastasia Velalopoulou

Explore the profile of Anastasia Velalopoulou including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 503
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Recent Articles
1.
Verginadis I, Velalopoulou A, Kim M, Kim K, Paraskevaidis I, Bell B, et al.
Radiother Oncol . 2025 Jan; 205:110744. PMID: 39880309
Background And Purpose: The normal tissue sparing afforded by FLASH radiotherapy is being intensely investigated for potential clinical translation. Here, we studied the effects of FLASH proton radiotherapy (F-PRT) in...
2.
Lim T, Morral C, Verginadis I, Kim K, Luo L, Foley C, et al.
bioRxiv . 2024 Sep; PMID: 39229237
Ultra-high dose rate ("FLASH") radiotherapy (>40-60 Gy/s) is a promising new radiation modality currently in human clinical trials. Previous studies showed that FLASH proton radiotherapy (FR) improves toxicity of normal...
3.
Verginadis I, Velalopoulou A, Kim M, Kim K, Paraskevaidis I, Bell B, et al.
bioRxiv . 2024 Jul; PMID: 39026805
Background And Purpose: The normal tissue sparing afforded by FLASH radiotherapy (RT) is being intensely investigated for potential clinical translation. Here, we studied the effects of FLASH proton RT (F-PRT)...
4.
Logotheti S, Pavlopoulou A, Rudsari H, Galow A, Kafali Y, Kyrodimos E, et al.
Pharmacol Ther . 2024 Jun; 260:108670. PMID: 38823489
Advances in cancer therapeutics have improved patient survival rates. However, cancer survivors may suffer from adverse events either at the time of therapy or later in life. Cardiovascular diseases (CVD)...
5.
Chowdhury P, Velalopoulou A, Verginadis I, Morcos G, Loo P, Kim M, et al.
Mol Cancer Ther . 2024 Apr; 23(6):877-889. PMID: 38593239
Head and neck cancer radiotherapy often damages salivary glands and oral mucosa, severely negatively impacting patients' quality of life. The ability of FLASH proton radiotherapy (F-PRT) to decrease normal tissue...
6.
Dreyfuss A, Velalopoulou A, Avgousti H, Bell B, Verginadis I
Front Oncol . 2022 Oct; 12:920867. PMID: 36313656
Radiation therapy (RT) is an important modality in cancer treatment with >50% of cancer patients undergoing RT for curative or palliative intent. In patients with breast, lung, and esophageal cancer,...
7.
Verginadis I, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, et al.
Nat Cell Biol . 2022 Jun; 24(6):940-953. PMID: 35654839
Bidirectional signalling between the tumour and stroma shapes tumour aggressiveness and metastasis. ATF4 is a major effector of the Integrated Stress Response, a homeostatic mechanism that couples cell growth and...
8.
Van Slyke A, Khatib M, Velalopoulou A, Diffenderfer E, Shoniyozov K, Kim M, et al.
Radiat Res . 2022 May; 198(2):181-189. PMID: 35640166
FLASH is a high-dose-rate form of radiation therapy that has the reported ability, compared with conventional dose rates, to spare normal tissues while being equipotent in tumor control, thereby increasing...
9.
Nikitaki Z, Velalopoulou A, Zanni V, Tremi I, Havaki S, Kokkoris M, et al.
Expert Rev Mol Med . 2022 Mar; 24:e15. PMID: 35357290
DNA damage and repair studies are at the core of the radiation biology field and represent also the fundamental principles informing radiation therapy (RT). DNA damage levels are a function...
10.
Khatib M, Van Slyke A, Velalopoulou A, Kim M, Shoniyozov K, Rao Allu S, et al.
Int J Radiat Oncol Biol Phys . 2022 Mar; 113(3):624-634. PMID: 35314293
Purpose: Radiation therapy delivered at ultrafast dose rates, known as FLASH RT, has been shown to provide a therapeutic advantage compared with conventional radiation therapy by selectively protecting normal tissues....