Anan Yu
Overview
Explore the profile of Anan Yu including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
445
Followers
0
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Recent Articles
1.
Xiao Q, Cruz G, Botham R, Fox S, Yu A, Allen S, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(32):e2322500121.
PMID: 39074281
Macroautophagy is a conserved cellular degradation pathway that, upon upregulation, confers resilience toward various stress conditions, including protection against proteotoxicity associated with neurodegenerative diseases, leading to cell survival. Monitoring autophagy...
2.
Zhang M, Yu A, Wu H, Xiong X, Li J, Chen L
Anim Sci J
. 2024 Apr;
95(1):e13946.
PMID: 38651265
This study explored the effects of a Bacillus subtilis and Lactobacillus acidophilus mixture containing the co-fermented products of the two probiotics on growth performance, serum immunity and cecal microbiota of...
3.
Capano L, Sato C, Ficulle E, Yu A, Horie K, Kwon J, et al.
Cell Stem Cell
. 2022 Jun;
29(6):918-932.e8.
PMID: 35659876
Tau is a microtubule-binding protein expressed in neurons, and the equal ratios between 4-repeat (4R) and 3-repeat (3R) isoforms are maintained in normal adult brain function. Dysregulation of 3R:4R ratio...
4.
Yang H, Zheng H, Pan Y, Zhang W, Yang M, Du H, et al.
Proteomics
. 2021 Sep;
21(20):e2100007.
PMID: 34482643
Methionine (Met) and cystine (CySS) are key sulfur donors in cell metabolism and are important nutrients for sustaining tumor growth; however, the molecular effects associated with their deprivation remain to...
5.
Sinnige T, Yu A, Morimoto R
Adv Exp Med Biol
. 2020 Apr;
1243:53-68.
PMID: 32297211
Protein homeostasis (Proteostasis) is essential for correct and efficient protein function within the living cell. Among the critical components of the Proteostasis Network (PN) are molecular chaperones that serve widely...
6.
Yu A, Fox S, Cavallini A, Kerridge C, ONeill M, Wolak J, et al.
J Biol Chem
. 2019 Apr;
294(19):7917-7930.
PMID: 30936201
Tauopathies are a diverse class of neurodegenerative diseases characterized by the formation of insoluble tau aggregates and the loss of cellular function and neuronal death. Tau inclusions have been shown...
7.
Yu A, Lv J, Yuan F, Xia Z, Fan K, Chen G, et al.
Int J Nanomedicine
. 2017 Dec;
12:8353-8362.
PMID: 29200847
Purpose: This study aimed to develop a novel methoxy poly(ethylene glycol)-poly(lactide) (mPEG-PLA)/D-α-tocopherol polyethylene glycol 1000 succinate (TPGS) mixed micelle drug delivery system to improve lamotrigine (LTG) distribution in the hippocampus....
8.
Huang S, Yu X, Yang L, Song F, Chen G, Lv Z, et al.
Eur J Pharm Sci
. 2014 Jul;
63:187-98.
PMID: 25063034
Objective: In order to develop and compare mPEG-PLA micelles and mPEG-PLA/TPGS mixed micelles, with the intention to develop a highly efficient formulation for nimodipine (NIM), NIM-loaded micelles and mixed micelles...
9.
Bocking T, Aguet F, Rapoport I, Banzhaf M, Yu A, Zeeh J, et al.
Structure
. 2014 May;
22(6):819-29.
PMID: 24815030
Clathrin-coated vesicles are major carriers of vesicular traffic in eukaryotic cells. This endocytic pathway relies on cycles of clathrin coat assembly and Hsc70-mediated disassembly. Here we identify histidine residues as...
10.
Yu A, Shibata Y, Shah B, Calamini B, Lo D, Morimoto R
Proc Natl Acad Sci U S A
. 2014 Apr;
111(15):E1481-90.
PMID: 24706768
Protein conformational diseases exhibit complex pathologies linked to numerous molecular defects. Aggregation of a disease-associated protein causes the misfolding and aggregation of other proteins, but how this interferes with diverse...