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Anabela Bensimon-Brito

Explore the profile of Anabela Bensimon-Brito including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 332
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Recent Articles
1.
Cardeira-da-Silva J, Bensimon-Brito A, Tarasco M, Brandao A, Rosa J, Borbinha J, et al.
Proc Natl Acad Sci U S A . 2022 Nov; 119(48):e2209231119. PMID: 36417434
The shaping of bone structures relies on various cell types and signaling pathways. Here, we use the zebrafish bifurcating fin rays during regeneration to investigate bone patterning. We found that...
2.
Brandao A, Borbinha J, Pereira T, Brito P, Lourenco R, Bensimon-Brito A, et al.
Elife . 2022 Aug; 11. PMID: 35993337
Regeneration depends on the ability of mature cells at the injury site to respond to injury, generating tissue-specific progenitors that incorporate the blastema and proliferate to reconstitute the original organ...
3.
Tarasco M, Gavaia P, Bensimon-Brito A, Cordelieres F, Santos T, Martins G, et al.
Chemosphere . 2022 Jun; 303(Pt 3):135198. PMID: 35660050
The presence of microplastics in the aquatic ecosystem represents a major issue for the environment and human health. The capacity of organic pollutants to adsorb onto microplastic particles raises additional...
4.
Bensimon-Brito A, Boezio G, Cardeira-da-Silva J, Wietelmann A, Ramkumar S, Lundegaard P, et al.
Cardiovasc Res . 2021 Oct; 118(12):2665-2687. PMID: 34609500
Aims: Mammalian models have been instrumental in investigating adult heart function and human disease. However, electrophysiological differences with human hearts and high costs motivate the need for non-mammalian models. The...
5.
Tarasco M, Gavaia P, Bensimon-Brito A, Cardeira-da-Silva J, Ramkumar S, Cordelieres F, et al.
Ecotoxicol Environ Saf . 2021 Oct; 226:112838. PMID: 34607190
Persistent and ubiquitous organic pollutants, such as the polycyclic aromatic hydrocarbon benzo[⍺]pyrene (BaP), represent a major threat to aquatic organisms and human health. Beside some well-documented adverse effects on the...
6.
Gentile A, Bensimon-Brito A, Priya R, Maischein H, Piesker J, Guenther S, et al.
Elife . 2021 Jun; 10. PMID: 34152269
The transcription factor Snai1, a well-known regulator of epithelial-to-mesenchymal transition, has been implicated in early cardiac morphogenesis as well as in cardiac valve formation. However, a role for Snai1 in...
7.
Boezio G, Bensimon-Brito A, Piesker J, Guenther S, Helker C, Stainier D
Elife . 2020 Sep; 9. PMID: 32990594
The development of the cardiac outflow tract (OFT), which connects the heart to the great arteries, relies on a complex crosstalk between endothelial (ECs) and smooth muscle (SMCs) cells. Defects...
8.
Gunawan F, Gentile A, Gauvrit S, Stainier D, Bensimon-Brito A
Circ Res . 2020 Feb; 126(8):968-984. PMID: 32070236
Rationale: The transcription factor NFATC1 (nuclear factor of activated T-cell 1) has been implicated in cardiac valve formation in humans and mice, but we know little about the underlying mechanisms....
9.
Bensimon-Brito A, Ramkumar S, Boezio G, Guenther S, Kuenne C, Helker C, et al.
Dev Cell . 2019 Dec; 52(1):9-20.e7. PMID: 31786069
Cardiac valve disease can lead to severe cardiac dysfunction and is thus a frequent cause of morbidity and mortality. Its main treatment is valve replacement, which is currently greatly limited...
10.
Brandao A, Bensimon-Brito A, Lourenco R, Borbinha J, Soares A, Mateus R, et al.
J Cell Sci . 2019 Oct; 132(22). PMID: 31636113
Osteoblast differentiation is a key process for bone homeostasis and repair. Multiple signalling pathways have been associated with osteoblast differentiation, yet much remains unknown on how this process is regulated...