Ana Maria Gonzalez-Angulo
Overview
Explore the profile of Ana Maria Gonzalez-Angulo including associated specialties, affiliations and a list of published articles.
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76
Citations
6128
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Recent Articles
11.
LYN-activating mutations mediate antiestrogen resistance in estrogen receptor-positive breast cancer
Schwarz L, Fox E, Balko J, Garrett J, Kuba M, Estrada M, et al.
J Clin Invest
. 2014 Nov;
124(12):5490-502.
PMID: 25401474
Estrogen receptor-positive (ER(+)) breast cancers adapt to hormone deprivation and become resistant to antiestrogen therapy. Here, we performed deep sequencing on ER(+) tumors that remained highly proliferative after treatment with...
12.
Zhou H, Mohamedali K, Gonzalez-Angulo A, Cao Y, Migliorini M, Cheung L, et al.
Mol Cancer Ther
. 2014 Sep;
13(11):2688-705.
PMID: 25239934
The cytokine TWEAK and its receptor, Fn14, have emerged as potentially valuable targets for cancer therapy. Granzyme B (GrB)-containing Fn14-targeted constructs were generated containing either the Fn14 ligand TWEAK (GrB-TWEAK)...
13.
Zhou J, Rosen D, Andreou A, Brouquet A, Abbott D, Loyer E, et al.
Ann Diagn Pathol
. 2014 Sep;
18(5):266-70.
PMID: 25205085
Tumor response to neoadjuvant therapy is a significant predictive indicator of recurrence-free survival. We measured tumor response using residual tumor thickness at the tumor-normal tissue interface (TNI) and evaluated its...
14.
Debeb B, Gong Y, Atkinson R, Sneige N, Huo L, Gonzalez-Angulo A, et al.
J Exp Clin Cancer Res
. 2014 Jul;
33:58.
PMID: 25051981
Background: Enhancer of zeste homolog 2 (EZH2), a member of the polycomb group proteins, has been shown to promote cancer progression and breast cancer stem cell (CSC) expansion. Breast CSCs...
15.
OLeary P, Terrile M, Bajor M, Gaj P, Hennessy B, Mills G, et al.
Breast Cancer Res
. 2014 Jul;
16(4):R79.
PMID: 25011585
Introduction: Peroxiredoxin-1 (PRDX1) is a multifunctional protein, acting as a hydrogen peroxide (H2O2) scavenger, molecular chaperone and immune modulator. Although differential PRDX1 expression has been described in many tumors, the...
16.
Meric-Bernstam F, Akcakanat A, Chen H, Sahin A, Tarco E, Carkaci S, et al.
Clin Cancer Res
. 2014 Jun;
20(14):3870-83.
PMID: 24895461
Background: PI3K/Akt/mTOR signaling is being actively pursued as a therapeutic target for breast cancer. We sought to determine if tumor heterogeneity and biospecimen variables affect the evaluation of PI3K/Akt/mTOR pathway...
17.
Campos-Gomez S, Valero V, Flores-Arredondo J, Isassi-Chapa A, Rangel-Rodriguez I, Hortobagyi G, et al.
Breast J
. 2014 May;
20(4):434-6.
PMID: 24862358
No abstract available.
18.
Chae Y, Gonzalez-Angulo A
Oncologist
. 2014 Mar;
19(4):328-35.
PMID: 24664486
Breast cancer is one of the major public health problems of the Western world. Recent advances in genomics and gene expression-profiling approaches have enriched our understanding of this heterogeneous disease....
19.
Martinez de Duenas E, Hernandez A, Guerrero Zotano A, Carrion R, Chacon Lopez-Muniz J, Antolin Novoa S, et al.
Breast Cancer Res Treat
. 2014 Jan;
143(3):507-15.
PMID: 24414130
The objective of this study was to determine the conversion rate of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER) and progesterone receptor (PR) between primary tumors and...
20.
Jeselsohn R, Yelensky R, Buchwalter G, Frampton G, Meric-Bernstam F, Gonzalez-Angulo A, et al.
Clin Cancer Res
. 2014 Jan;
20(7):1757-1767.
PMID: 24398047
Purpose: We undertook this study to determine the prevalence of estrogen receptor (ER) α (ESR1) mutations throughout the natural history of hormone-dependent breast cancer and to delineate the functional roles...