Ana C da Silva Almeida
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Explore the profile of Ana C da Silva Almeida including associated specialties, affiliations and a list of published articles.
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7
Citations
193
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Recent Articles
1.
Alvarez S, da Silva Almeida A, Albero R, Biswas M, Barreto-Galvez A, Gunning T, et al.
Blood
. 2022 Mar;
139(23):3418-3429.
PMID: 35338774
The Plant Homeodomain 6 gene (PHF6) encodes a nucleolar and chromatin-associated leukemia tumor suppressor with proposed roles in transcription regulation. However, specific molecular mechanisms controlled by PHF6 remain rudimentarily understood....
2.
Huckins L, Chatzinakos C, Breen M, Hartmann J, Klengel T, da Silva Almeida A, et al.
Cell Rep
. 2020 Jun;
31(9):107716.
PMID: 32492425
To reveal post-traumatic stress disorder (PTSD) genetic risk influences on tissue-specific gene expression, we use brain and non-brain transcriptomic imputation. We impute genetically regulated gene expression (GReX) in 29,539 PTSD...
3.
Cortes J, Ambesi-Impiombato A, Couronne L, Quinn S, Kim C, da Silva Almeida A, et al.
Cancer Cell
. 2018 Feb;
33(2):259-273.e7.
PMID: 29398449
Angioimmunoblastic T cell lymphoma (AITL) is an aggressive tumor derived from malignant transformation of T follicular helper (Tfh) cells. AITL is characterized by loss-of-function mutations in Ten-Eleven Translocation 2 (TET2)...
4.
da Silva Almeida A, Hocking H, Boelens R, Strous G, van Rossum A
Biochem J
. 2013 Apr;
453(2):291-301.
PMID: 23607312
GH (growth hormone) binding to the GHR (GH receptor) triggers essential signalling pathways that promote growth and metabolic regulation. The sensitivity of the cells to GH is mainly controlled by...
5.
Slotman J, da Silva Almeida A, Hassink G, van de Ven R, van Kerkhof P, Kuiken H, et al.
J Biol Chem
. 2012 Mar;
287(19):15533-43.
PMID: 22433856
Growth hormone receptor (GHR) endocytosis is a highly regulated process that depends on the binding and activity of the multimeric ubiquitin ligase, SCF(βTrCP) (Skp Cullin F-box). Despite a specific interaction...
6.
da Silva Almeida A, Strous G, van Rossum A
Mol Endocrinol
. 2011 Oct;
26(1):165-77.
PMID: 22034227
The physiological roles of GH are broad and include metabolism regulation and promotion of somatic growth. Therefore, the responsiveness of cells to GH must be tightly regulated. This is mainly...
7.
Putters J, da Silva Almeida A, van Kerkhof P, van Rossum A, Gracanin A, Strous G
PLoS One
. 2011 Feb;
6(2):e14676.
PMID: 21347402
Background: Length and intensity of signal transduction via cytokine receptors is precisely regulated. Degradation of certain cytokine receptors is mediated by the ubiquitin ligase SCF(βTrCP). In several instances, Janus kinase...