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Amy E Clewell

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Citations 99
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Recent Articles
1.
Murbach T, Glavits R, Endres J, Clewell A, Hirka G, Vertesi A, et al.
Toxicol Rep . 2020 Sep; 7:1242-1254. PMID: 32995299
Humic substances are ubiquitous in soils and waters. These complex superstructures are derived from the decomposition of dead plant and animal matter and are vital to soil health. Their heterogenous...
2.
Murbach T, Glavits R, Endres J, Clewell A, Hirka G, Vertesi A, et al.
J Toxicol . 2020 Jan; 2019:4981420. PMID: 31911801
Methylliberine (CAS 51168-26-4), a methoxiuric acid, is a caffeine metabolite present at low levels in various plants; however, very little has been published regarding this compound and we could find...
3.
Reddeman R, Glavits R, Endres J, Clewell A, Hirka G, Vertesi A, et al.
J Toxicol . 2019 Aug; 2019:4763015. PMID: 31467524
A battery of OECD- and GLP-compliant toxicological studies was performed on mango leaf extract () containing 60% mangiferin (MLE). No evidence of genotoxicity was found in a bacterial reverse mutation...
4.
Palmer P, Bryson J, Clewell A, Endres J, Hirka G, Vertesi A, et al.
Regul Toxicol Pharmacol . 2019 Jan; 103:140-149. PMID: 30684565
A battery of toxicological studies was conducted to aid in the safety assessment of an ethanolic extract of Ageratum conyzoides for use as an ingredient in food. In accordance with...
5.
Marx T, Reddeman R, Clewell A, Endres J, Beres E, Vertesi A, et al.
J Toxicol . 2018 Jul; 2018:8143582. PMID: 29977291
A battery of toxicological studies was conducted on a supercritical CO extract of the aerial parts of the plant, containing approximately 25% cannabinoids. No evidence of genotoxicity was found in...
6.
Murbach T, Glavits R, Hirka G, Endres J, Clewell A, Szakonyine I
Toxicol Rep . 2017 Sep; 4:494-501. PMID: 28959679
Fernblock is a standardized commercial aqueous extraction of the leaves of the tropical fern promoted as an orally active photoprotective substance. In a previous battery of toxicological tests on Fernblock,...
7.
Marx T, Glavits R, Endres J, Palmer P, Clewell A, Murbach T, et al.
Int J Toxicol . 2016 Oct; 35(6):683-691. PMID: 27733446
Morus alba L. (white mulberry) leaves are one of the oldest recognized traditional Chinese medicines. More recently, M alba leaves and their constituents, particularly iminosugars (or azasugars), have garnered attention...
8.
Clewell A, Beres E, Vertesi A, Glavits R, Hirka G, Endres J, et al.
Int J Toxicol . 2015 Dec; 35(2):208-21. PMID: 26658007
A battery of toxicological studies was conducted to investigate the genotoxicity and repeated-dose oral toxicity of Bonolive™, a proprietary water-soluble extract of the leaves of the olive tree (Olea europaea...
9.
Murbach T, Beres E, Vertesi A, Glavits R, Hirka G, Endres J, et al.
Food Chem Toxicol . 2015 Nov; 86:328-41. PMID: 26585922
A battery of toxicological studies was conducted in accordance with internationally accepted standards to investigate the genotoxicity and repeated-dose oral toxicity of Fernblock(®), a commercial aqueous extraction of the leaves...
10.
Odendaal A, Deshmukh N, Marx T, Schauss A, Endres J, Clewell A
Int J Toxicol . 2013 Jun; 32(5):385-94. PMID: 23771637
This toxicological assessment evaluated the safety of a hydroethanolic extract prepared from Caralluma fimbriata (CFE), a dietary supplement marketed worldwide as an appetite suppressant. Studies included 2 in vitro genotoxicity...