Amy Andreucci
Overview
Explore the profile of Amy Andreucci including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
125
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0
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Recent Articles
1.
Liu Y, Andreucci A, Iwamoto N, Yin Y, Yang H, Liu F, et al.
Mol Ther Nucleic Acids
. 2022 May;
28:558-570.
PMID: 35592494
A large hexanucleotide (GC) repeat expansion in the first intronic region of is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Several mechanisms have...
2.
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS
Kandasamy P, Liu Y, Aduda V, Akare S, Alam R, Andreucci A, et al.
Nucleic Acids Res
. 2022 Feb;
50(10):5401-5423.
PMID: 35106589
Attaining sufficient tissue exposure at the site of action to achieve the desired pharmacodynamic effect on a target is an important determinant for any drug discovery program, and this can...
3.
Deprey K, Batistatou N, Debets M, Godfrey J, VanderWall K, Miles R, et al.
ACS Chem Biol
. 2022 Jan;
17(2):348-360.
PMID: 35034446
A major obstacle in the development of effective oligonucleotide therapeutics is a lack of understanding about their cytosolic and nuclear penetration. To address this problem, we have applied the chloroalkane...
4.
Koncarevic A, Kajimura S, Cornwall-Brady M, Andreucci A, Pullen A, Sako D, et al.
Endocrinology
. 2012 May;
153(7):3133-46.
PMID: 22549226
Obesity results from disproportionately high energy intake relative to energy expenditure. Many therapeutic strategies have focused on the intake side of the equation, including pharmaceutical targeting of appetite and digestion....
5.
McCarthy K, McDevit D, Andreucci A, Reeves R, Nikolajczyk B
J Biol Chem
. 2003 Aug;
278(43):42106-14.
PMID: 12907668
The immunoglobulin heavy chain enhancer, or mu enhancer, is required for B cell development. Only the appropriate combination of transcription factors results in B cell-specific enhancer activation. HMGA1 (formerly (HMG-I(Y))...
6.
Andreucci A, Reeves R, McCarthy K, Nikolajczyk B
Biochem Biophys Res Commun
. 2002 Mar;
292(2):427-33.
PMID: 11906180
The immunoglobulin mu intronic enhancer is a potent B cell-specific transcriptional activator. The enhancer is activated by the appropriate combination of transcription factors, amongst which are ets and bHLH proteins....