Amulya Sreekumar
Overview
Explore the profile of Amulya Sreekumar including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
109
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Recent Articles
1.
Sreekumar A, Lu M, Choudhury B, Pan T, Pant D, Lawrence-Paul M, et al.
Cancer Cell
. 2023 Dec;
42(1):52-69.e7.
PMID: 38065100
Breast cancer mortality results from incurable recurrences thought to be seeded by dormant, therapy-refractory residual tumor cells (RTCs). Understanding the mechanisms enabling RTC survival is therefore essential for improving patient...
2.
Dalla E, Sreekumar A, Aguirre-Ghiso J, Chodosh L
Cold Spring Harb Perspect Med
. 2023 Apr;
13(11.
PMID: 37037598
The pattern of delayed recurrence in a subset of breast cancer patients has long been explained by a model that incorporates a variable period of cellular or tumor mass dormancy...
3.
Chen S, Paul M, Sterner C, Belka G, Wang D, Xu P, et al.
Breast Cancer Res
. 2023 Jan;
25(1):1.
PMID: 36597146
Background: Breast cancer mortality is principally due to recurrent disease that becomes resistant to therapy. We recently identified copy number (CN) gain of the putative membrane progesterone receptor PAQR8 as...
4.
Sreekumar A, Toneff M, Toh E, Roarty K, Creighton C, Belka G, et al.
Dev Cell
. 2017 Nov;
43(4):436-448.e6.
PMID: 29103953
Puberty is characterized by dynamic tissue remodeling in the mammary gland involving ductal elongation, resolution into the mature epithelial bilayer, and lumen formation. To decipher the cellular mechanisms underlying these...
5.
Paine I, Chauviere A, Landua J, Sreekumar A, Cristini V, Rosen J, et al.
PLoS Comput Biol
. 2016 Apr;
12(4):e1004839.
PMID: 27115287
Mathematics is often used to model biological systems. In mammary gland development, mathematical modeling has been limited to acinar and branching morphogenesis and breast cancer, without reference to normal duct...
6.
Sreekumar A, Roarty K, Rosen J
Endocr Relat Cancer
. 2015 Jul;
22(6):T161-76.
PMID: 26206777
The mammary gland is a dynamic organ that undergoes extensive morphogenesis during the different stages of embryonic development, puberty, estrus, pregnancy, lactation and involution. Systemic and local cues underlie this...
7.
Farrall A, Riemer P, Leushacke M, Sreekumar A, Grimm C, Herrmann B, et al.
Int J Cancer
. 2012 Feb;
131(10):2242-52.
PMID: 22344573
Cellular hierarchies and signals that govern stemness and differentiation of intestinal adenoma cells are not well defined. In this study, we used organotypic culture to investigate the impact of β-catenin...