Amit Zeisel
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Explore the profile of Amit Zeisel including associated specialties, affiliations and a list of published articles.
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41
Citations
8109
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Recent Articles
11.
Codeluppi S, Borm L, Zeisel A, La Manno G, van Lunteren J, Svensson C, et al.
Nat Methods
. 2018 Nov;
15(11):932-935.
PMID: 30377364
Global efforts to create a molecular census of the brain using single-cell transcriptomics are producing a large catalog of molecularly defined cell types. However, spatial information is lacking and new...
12.
Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq
Munoz-Manchado A, Bengtsson Gonzales C, Zeisel A, Munguba H, Bekkouche B, Skene N, et al.
Cell Rep
. 2018 Aug;
24(8):2179-2190.e7.
PMID: 30134177
Striatal locally projecting neurons, or interneurons, act on nearby circuits and shape functional output to the rest of the basal ganglia. We performed single-cell RNA sequencing of striatal cells enriching...
13.
Zeisel A, Hochgerner H, Lonnerberg P, Johnsson A, Memic F, van der Zwan J, et al.
Cell
. 2018 Aug;
174(4):999-1014.e22.
PMID: 30096314
The mammalian nervous system executes complex behaviors controlled by specialized, precisely positioned, and interacting cell types. Here, we used RNA sequencing of half a million single cells to create a...
14.
La Manno G, Soldatov R, Zeisel A, Braun E, Hochgerner H, Petukhov V, et al.
Nature
. 2018 Aug;
560(7719):494-498.
PMID: 30089906
RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and throughput. However, this approach captures...
15.
Haring M, Zeisel A, Hochgerner H, Rinwa P, Jakobsson J, Lonnerberg P, et al.
Nat Neurosci
. 2018 Apr;
21(6):869-880.
PMID: 29686262
The dorsal horn of the spinal cord is critical to processing distinct modalities of noxious and innocuous sensation, but little is known of the neuronal subtypes involved, hampering efforts to...
16.
Fuks G, Elgart M, Amir A, Zeisel A, Turnbaugh P, Soen Y, et al.
Microbiome
. 2018 Jan;
6(1):17.
PMID: 29373999
Background: Most of our knowledge about the remarkable microbial diversity on Earth comes from sequencing the 16S rRNA gene. The use of next-generation sequencing methods has increased sample number and...
17.
Hochgerner H, Zeisel A, Lonnerberg P, Linnarsson S
Nat Neurosci
. 2018 Jan;
21(2):290-299.
PMID: 29335606
The dentate gyrus of the hippocampus is a brain region in which neurogenesis persists into adulthood; however, the relationship between developmental and adult dentate gyrus neurogenesis has not been examined...
18.
Hochgerner H, Lonnerberg P, Hodge R, Mikes J, Heskol A, Hubschle H, et al.
Sci Rep
. 2017 Nov;
7(1):16327.
PMID: 29180631
Single-cell RNA-seq has become routine for discovering cell types and revealing cellular diversity, but archived human brain samples still pose a challenge to current high-throughput platforms. We present STRT-seq-2i, an...
19.
Golan-Lavi R, Giacomelli C, Fuks G, Zeisel A, Sonntag J, Sinha S, et al.
Cell Rep
. 2017 Mar;
18(13):3129-3142.
PMID: 28355565
Protein responses to extracellular cues are governed by gene transcription, mRNA degradation and translation, and protein degradation. In order to understand how these time-dependent processes cooperate to generate dynamic responses,...
20.
Romanov R, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, et al.
Nat Neurosci
. 2016 Dec;
20(2):176-188.
PMID: 27991900
The hypothalamus contains the highest diversity of neurons in the brain. Many of these neurons can co-release neurotransmitters and neuropeptides in a use-dependent manner. Investigators have hitherto relied on candidate...