Amit Rupani
Overview
Explore the profile of Amit Rupani including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
41
Followers
0
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Recent Articles
1.
McAfee J, Alban T, Makarov V, Rupani A, Parthasarathy P, Tu Z, et al.
Lab Invest
. 2024 Nov;
105(2):102183.
PMID: 39532239
Superficial malignant peripheral nerve sheath tumors (SF-MPNSTs) are rare cancers and can be difficult to distinguish from spindle cell (SCM) or desmoplastic (DM) melanomas. Their biology is poorly understood. We...
2.
Ta H, Roy D, Zhang K, Alban T, Juric I, Dong J, et al.
Sci Immunol
. 2024 May;
9(95):eadi7418.
PMID: 38758807
Immune checkpoint blockade is a promising approach to activate antitumor immunity and improve the survival of patients with cancer. V-domain immunoglobulin suppressor of T cell activation (VISTA) is an immune...
3.
Zhang K, Zakeri A, Alban T, Dong J, Ta H, Zalavadia A, et al.
Cell Rep
. 2024 Jan;
43(1):113661.
PMID: 38175754
Myeloid-derived suppressor cells (MDSCs) impair antitumor immune responses. Identifying regulatory circuits during MDSC development may bring new opportunities for therapeutic interventions. We report that the V-domain suppressor of T cell...
4.
Wilkerson A, Parthasarathy P, Stabellini N, Mitchell C, Pavicic Jr P, Fu P, et al.
Clin Cancer Res
. 2023 Oct;
30(1):82-93.
PMID: 37882661
Purpose: A single arm, phase II trial of carboplatin, nab-paclitaxel, and pembrolizumab (CNP) in metastatic triple-negative breast cancer (mTNBC) was designed to evaluate overall response rate (ORR), progression-free survival (PFS),...
5.
Pavicic Jr P, Rayman P, Swaidani S, Rupani A, Makarov V, Tannenbaum C, et al.
Oncoimmunology
. 2023 Apr;
12(1):2198185.
PMID: 37066116
The tumor microenvironment (TME) in ovarian cancer (OC) is characterized by immune suppression, due to an abundance of suppressive immune cells populations. To effectively enhance the activity of immune checkpoint...
6.
Noto F, Sangodkar J, Adedeji B, Moody S, McClain C, Tong M, et al.
PLoS One
. 2020 Oct;
15(10):e0240169.
PMID: 33027304
We have created the immunodeficient SRG rat, a Sprague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. This model has been tested and validated...
7.
Sahinoz M, Khairi S, Cuttitta A, Brady G, Rupani A, Meral R, et al.
Clin Diabetes Endocrinol
. 2018 Apr;
4:6.
PMID: 29610677
Background: Juvenile dermatomyositis (JDM) is an auto-immune muscle disease which presents with skin manifestations and muscle weakness. At least 10% of the patients with JDM present with acquired lipodystrophy. Laminopathies...