Amit Gaba
Overview
Explore the profile of Amit Gaba including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
145
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Gaba A, Yousefi M, Bhattacharjee S, Chelico L
J Virol
. 2024 Dec;
99(1):e0160624.
PMID: 39714157
Several APOBEC3 enzymes restrict HIV-1 by deaminating cytosine to form uracil in single-stranded proviral (-)DNA. However, HIV-1 Vif counteracts their activity by inducing their proteasomal degradation. This counteraction by Vif...
2.
Jang G, Annan Sudarsan A, Shayeganmehr A, Prando Munhoz E, Lao R, Gaba A, et al.
Mol Cell Proteomics
. 2024 Mar;
23(5):100755.
PMID: 38548018
Human APOBEC3 enzymes are a family of single-stranded (ss)DNA and RNA cytidine deaminases that act as part of the intrinsic immunity against viruses and retroelements. These enzymes deaminate cytosine to...
3.
Jang G, Annan Sudarsan A, Shayeganmehr A, Prando Munhoz E, Lao R, Gaba A, et al.
bioRxiv
. 2024 Feb;
PMID: 38370690
Human APOBEC3 enzymes are a family of single-stranded (ss)DNA and RNA cytidine deaminases that act as part of the intrinsic immunity against viruses and retroelements. These enzymes deaminate cytosine to...
4.
Yousefi M, Annan Sudarsan A, Gaba A, Chelico L
Viruses
. 2023 Feb;
15(2).
PMID: 36851677
The seven human APOBEC3 enzymes (APOBEC3A through H, excluding E) are host restriction factors. Most of the APOBEC3 enzymes can restrict HIV-1 replication with different efficiencies. The HIV-1 Vif protein...
5.
Gaba A, Hix M, Suhail S, Flath B, Boysan B, Williams D, et al.
J Mol Biol
. 2021 Oct;
433(24):167306.
PMID: 34666043
The APOBEC3 (A3) family of single-stranded DNA cytidine deaminases are host restriction factors that inhibit lentiviruses, such as HIV-1, in the absence of the Vif protein that causes their degradation....
6.
Gaba A, Flath B, Chelico L
Viruses
. 2021 Jul;
13(6).
PMID: 34200141
The transmission of viruses from animal hosts into humans have led to the emergence of several diseases. Usually these cross-species transmissions are blocked by host restriction factors, which are proteins...
7.
McDonnell M, Karvonen S, Gaba A, Flath B, Chelico L, Emerman M
PLoS Pathog
. 2021 Jun;
17(6):e1009523.
PMID: 34170969
The APOBEC3 (A3) genes encode cytidine deaminase proteins with potent antiviral and anti-retroelement activity. This locus is characterized by duplication, recombination, and deletion events that gave rise to the seven...
8.
Nchioua R, Kmiec D, Gaba A, Sturzel C, Follack T, Patrick S, et al.
J Virol
. 2021 Jun;
95(17):e0080821.
PMID: 34132575
Simian immunodeficiency virus infecting sooty mangabeys (SIVsmm) has been transmitted to humans on at least nine occasions, giving rise to human immunodeficiency virus type 2 (HIV-2) groups A to I....
9.
Lu Y, Landreth S, Liu G, Brownlie R, Gaba A, van Drunen Littel-van den Hurk S, et al.
Vaccine
. 2020 Feb;
38(10):2387-2395.
PMID: 32014270
The highly pathogenic avian influenza (HPAI) H5N1 viruses and their spillover into the human population pose substantial economic and public health threats. Although antiviral drugs have some effect in treating...
10.
Yang H, Ito F, Wolfe A, Li S, Mohammadzadeh N, Love R, et al.
Nat Commun
. 2020 Feb;
11(1):632.
PMID: 32005813
APOBEC3G, a member of the double-domain cytidine deaminase (CD) APOBEC, binds RNA to package into virions and restrict HIV-1 through deamination-dependent or deamination-independent inhibition. Mainly due to lack of a...