Amir Dailamy
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Explore the profile of Amir Dailamy including associated specialties, affiliations and a list of published articles.
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9
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92
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Recent Articles
1.
Nourreddine S, Doctor Y, Dailamy A, Forget A, Lee Y, Chinn B, et al.
bioRxiv
. 2024 Nov;
PMID: 39574586
Towards comprehensively investigating the genotype-phenotype relationships governing the human pluripotent stem cell state, we generated an expressed genome-scale CRISPRi Perturbation Cell Atlas in KOLF2.1J human induced pluripotent stem cells (hiPSCs)...
2.
Dailamy A, Lyu W, Nourreddine S, Tong M, Rainaldi J, McDonald D, et al.
Nat Commun
. 2024 Nov;
15(1):9818.
PMID: 39537590
Adenosine deaminases acting on RNA (ADARs) impact diverse cellular processes and pathological conditions, but their functions in early cell-fate specification remain less understood. To gain insights here, we began by...
3.
Tong M, Palmer N, Dailamy A, Kumar A, Khaliq H, Han S, et al.
Nat Biomed Eng
. 2024 Aug;
9(1):109-126.
PMID: 39187662
Circularization can improve RNA persistence, yet simple and scalable approaches to achieve this are lacking. Here we report two methods that facilitate the pursuit of circular RNAs (cRNAs): cRNAs developed...
4.
Clark T, Mohan J, Schaffer L, Obernier K, Al Manir S, Churas C, et al.
bioRxiv
. 2024 Jun;
PMID: 38826258
This article describes the Cell Maps for Artificial Intelligence (CM4AI) project and its goals, methods, standards, current datasets, software tools , status, and future directions. CM4AI is the in the...
5.
Parekh U, McDonald D, Dailamy A, Wu Y, Cordes T, Zhang K, et al.
iScience
. 2021 Oct;
24(10):103149.
PMID: 34646987
Deconstructing tissue-specific effects of genes and variants on proliferation is critical to understanding cellular transformation and systematically selecting cancer therapeutics. This requires scalable methods for multiplexed genetic screens tracking fitness...
6.
Dailamy A, Parekh U, Katrekar D, Kumar A, McDonald D, Moreno A, et al.
Stem Cell Reports
. 2021 Sep;
16(10):2432-2441.
PMID: 34559998
Pluripotent stem cell-derived organoids have transformed our ability to recreate complex three-dimensional models of human tissue. However, the directed differentiation methods used to create them do not afford the ability...
7.
M Moreno A, Aleman F, Catroli G, Hunt M, Hu M, Dailamy A, et al.
Sci Transl Med
. 2021 Mar;
13(584).
PMID: 33692134
Current treatments for chronic pain rely largely on opioids despite their substantial side effects and risk of addiction. Genetic studies have identified in humans key targets pivotal to nociceptive processing....
8.
McDonald D, Wu Y, Dailamy A, Tat J, Parekh U, Zhao D, et al.
Cell
. 2020 Nov;
183(5):1402-1419.e18.
PMID: 33152263
We propose that the teratoma, a recognized standard for validating pluripotency in stem cells, could be a promising platform for studying human developmental processes. Performing single-cell RNA sequencing (RNA-seq) of...
9.
Hu M, Dailamy A, Lei X, Parekh U, McDonald D, Kumar A, et al.
Adv Healthc Mater
. 2018 Oct;
7(23):e1800845.
PMID: 30369101
Recent advances in tissue engineering and 3D bioprinting have enabled construction of cell-laden scaffolds containing perfusable vascular networks. Although these methods partially address the nutrient-diffusion limitations present in engineered tissues,...