Alvin Gomez
Overview
Explore the profile of Alvin Gomez including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
665
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Cho T, Bott D, Ahmed S, Hutin D, Gomez A, Tamblyn L, et al.
Int J Mol Sci
. 2019 May;
20(9).
PMID: 31083300
TCDD-inducible poly-ADP-ribose polymerase (TIPARP) is an aryl hydrocarbon receptor (AHR) target gene that functions as part of a negative feedback loop to repress AHR activity. mice exhibit increased sensitivity to...
2.
Gomez A, Bindesboll C, Satheesh S, Grimaldi G, Hutin D, MacPherson L, et al.
Biochem J
. 2018 Oct;
475(23):3827-3846.
PMID: 30373764
Here, we report the biochemical characterization of the mono-ADP-ribosyltransferase 2,3,7,8-tetrachlorodibenzo--dioxin poly-ADP-ribose polymerase (TIPARP/ARTD14/PARP7), which is known to repress aryl hydrocarbon receptor (AHR)-dependent transcription. We found that the nuclear localization of...
3.
Hutin D, Tamblyn L, Gomez A, Grimaldi G, Soedling H, Cho T, et al.
Toxicol Sci
. 2018 Jun;
165(2):347-360.
PMID: 29873790
The aryl hydrocarbon receptor (AHR) mediates the toxic effects of dioxin (2, 3, 7, 8-tetrachlorodibenzo-p-dioxin; TCDD), which includes thymic atrophy, steatohepatitis, and a lethal wasting syndrome in laboratory rodents. Although...
4.
Rogers S, de Souza A, Zago M, Iu M, Guerrina N, Gomez A, et al.
Sci Rep
. 2017 Jan;
7:40539.
PMID: 28079158
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically known for its toxic responses to man-made pollutants such as dioxin. More recently, the AhR has emerged as a...
5.
Sarill M, Zago M, Sheridan J, Nair P, Matthews J, Gomez A, et al.
Free Radic Biol Med
. 2015 Sep;
89:342-57.
PMID: 26408075
The aryl hydrocarbon receptor (AhR) is a ubiquitously expressed receptor/transcription factor that mediates toxicological responses of environmental contaminants such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Emerging evidence indicates that the AhR suppresses apoptosis...
6.
Ahmed S, Bott D, Gomez A, Tamblyn L, Rasheed A, Cho T, et al.
J Biol Chem
. 2015 May;
290(27):16824-40.
PMID: 25975270
The aryl hydrocarbon receptor (AHR) mediates the toxic effects of the environmental contaminant dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin; TCDD). Dioxin causes a range of toxic responses, including hepatic damage, steatohepatitis, and a lethal...
7.
Hecht E, Zago M, Sarill M, de Souza A, Gomez A, Matthews J, et al.
Toxicol Appl Pharmacol
. 2014 Sep;
280(3):511-25.
PMID: 25178717
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor implicated in the regulation of apoptosis and proliferation. Although activation of the AhR by xenobiotics such as dioxin inhibits the...
8.
Gomez A, Ingelman-Sundberg M
Expert Rev Clin Pharmacol
. 2014 Jan;
2(1):55-65.
PMID: 24422771
Our knowledge of epigenetics has increased in recent times and its role in various aspects of cellular physiology and disease cannot be overemphasized, even though many issues still need to...
9.
Gomez A, Nekvindova J, Travica S, Lee M, Johansson I, Edler D, et al.
Mol Pharmacol
. 2010 Sep;
78(6):1004-11.
PMID: 20805301
Cytochrome P450 2W1 (CYP2W1) is expressed at high levels in colorectal cancer cells. Moreover, we have shown previously that a higher tumor expression is associated with less survival. In this...
10.
Ingelman-Sundberg M, Gomez A
Pharmacogenomics
. 2010 Apr;
11(5):625-7.
PMID: 20415549
A significant number of instances of interindividual variability in drug response, where a clear phenotypic consequence is evident in the population, have not yet been associated with variations in gene...