Alvaro Cuesta-Dominguez
Overview
Explore the profile of Alvaro Cuesta-Dominguez including associated specialties, affiliations and a list of published articles.
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11
Citations
691
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Recent Articles
1.
Bisikirska B, Labella R, Cuesta-Dominguez A, Luo N, De Angelis J, Mosialou I, et al.
Sci Transl Med
. 2024 Oct;
16(769):eadj0085.
PMID: 39413162
Idiopathic osteoporosis (IOP) is a rare form of early-onset osteoporosis diagnosed in patients with no known metabolic or hormonal cause of bone loss and unknown pathogenesis. Patients with IOP commonly...
2.
Tikhonova A, Dolgalev I, Hu H, Sivaraj K, Hoxha E, Cuesta-Dominguez A, et al.
Nature
. 2019 Jul;
572(7767):E6.
PMID: 31296938
An Amendment to this paper has been published and can be accessed via a link at the top of the paper.
3.
Tikhonova A, Dolgalev I, Hu H, Sivaraj K, Hoxha E, Cuesta-Dominguez A, et al.
Nature
. 2019 Apr;
569(7755):222-228.
PMID: 30971824
The bone marrow microenvironment has a key role in regulating haematopoiesis, but its molecular complexity and response to stress are incompletely understood. Here we map the transcriptional landscape of mouse...
4.
Rodriguez-Bravo V, Pippa R, Song W, Carceles-Cordon M, Dominguez-Andres A, Fujiwara N, et al.
Cell
. 2018 Aug;
174(5):1200-1215.e20.
PMID: 30100187
Nuclear pore complexes (NPCs) regulate nuclear-cytoplasmic transport, transcription, and genome integrity in eukaryotic cells. However, their functional roles in cancer remain poorly understood. We interrogated the evolutionary transcriptomic landscape of...
5.
Young G, Terry S, Manganaro L, Cuesta-Dominguez A, Deikus G, Bernal-Rubio D, et al.
J Virol
. 2017 Oct;
92(1).
PMID: 29046457
Endogenous retroviruses (ERVs) occupy extensive regions of the human genome. Although many of these retroviral elements have lost their ability to replicate, those whose insertion took place more recently, such...
6.
Galan-Diez M, Cuesta-Dominguez A, Kousteni S
Cold Spring Harb Perspect Med
. 2017 Oct;
8(7).
PMID: 28963115
Hematopoietic stem cells (HSCs) interact dynamically with an intricate network of cells in the bone marrow (BM) microenvironment or niche. These interactions provide instructive cues that influence the production and...
7.
Terry S, Manganaro L, Cuesta-Dominguez A, Brinzevich D, Simon V, Mulder L
Virology
. 2017 Jun;
509:52-59.
PMID: 28605635
The human endogenous retroviruses (HERV)-K of the HML-2 group include full-length or near full-length elements encoding functional proteins, and are classified as type-1 or type-2 (type-1 has a deletion in...
8.
Cuesta-Dominguez A, Leon-Rico D, Alvarez L, Diez B, Bodega-Mayor I, Banos R, et al.
J Pathol
. 2015 Feb;
236(2):219-28.
PMID: 25664618
BCR-JAK2 is an infrequent gene fusion found in chronic/acute, myeloid/lymphoid Philadelphia chromosome-negative leukaemia. In this study, we demonstrated that in vivo expression of BCR-JAK2 in mice induces neoplasia, with fatal...
9.
Cuesta-Dominguez A, Ortega M, Ormazabal C, Santos-Roncero M, Galan-Diez M, Steegmann J, et al.
PLoS One
. 2012 Mar;
7(2):e32451.
PMID: 22384256
Chromosomal translocations in tumors frequently produce fusion genes coding for chimeric proteins with a key role in oncogenesis. Recent reports described a BCR-JAK2 fusion gene in fatal chronic and acute...
10.
Galan-Diez M, Arana D, Serrano-Gomez D, Kremer L, Casasnovas J, Ortega M, et al.
Infect Immun
. 2010 Jan;
78(4):1426-36.
PMID: 20100861
Innate immunity to Candida albicans depends upon the recognition of molecular patterns on the fungal cell wall. However, the masking of major components such as beta-glucan seems to be a...