Lara Manganaro
Overview
Explore the profile of Lara Manganaro including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
991
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Recent Articles
1.
Bozzi G, Centazzo M, Scaglioni S, Butta G, Saltini P, Liparoti A, et al.
AIDS
. 2024 Oct;
38(10):1601-1604.
PMID: 39422635
No abstract available.
2.
Mazzarella L, Santoro F, Ravasio R, Fumagalli V, Massa P, Rodighiero S, et al.
Sci Signal
. 2023 Dec;
16(816):eade0326.
PMID: 38113337
Innate immune responses to coronavirus infections are highly cell specific. Tissue-resident macrophages, which are infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients but are inconsistently infected in...
3.
Mancino M, Lai G, De Grossi F, Cuomo A, Manganaro L, Butta G, et al.
Microbiol Spectr
. 2023 Jun;
11(4):e0521122.
PMID: 37358411
FAM46C is a multiple myeloma (MM) tumor suppressor whose function is only starting to be elucidated. We recently showed that in MM cells FAM46C triggers apoptosis by inhibiting autophagy and...
4.
Centazzo M, Manganaro L, Alvisi G
Viruses
. 2023 Mar;
15(3).
PMID: 36992421
Human immunodeficiency virus 1 (HIV-1) viral protease (PR) is one of the most studied viral enzymes and a crucial antiviral target. Despite its well-characterized role in virion maturation, an increasing...
5.
Unali G, Crivicich G, Pagani I, Abou-Alezz M, Folchini F, Valeri E, et al.
EMBO J
. 2023 Mar;
42(10):e112234.
PMID: 36970857
The interferon-induced transmembrane proteins (IFITM) are implicated in several biological processes, including antiviral defense, but their modes of action remain debated. Here, taking advantage of pseudotyped viral entry assays and...
6.
Miluzio A, Cuomo A, Cordiglieri C, Donnici L, Pesce E, Bombaci M, et al.
EBioMedicine
. 2022 Dec;
87:104390.
PMID: 36584595
Background: The COVID-19 pandemic is an infectious disease caused by SARS-CoV-2. The first step of SARS-CoV-2 infection is the recognition of angiotensin-converting enzyme 2 (ACE2) receptors by the receptor-binding domain...
7.
Kim E, Manganaro L, Schotsaert M, Brown B, Mulder L, Simon V
Cell Rep Methods
. 2022 Jul;
2(6):100238.
PMID: 35784650
There is no cure for HIV infection, as the virus establishes a latent reservoir, which escapes highly active antiretroviral treatments. One major obstacle is the difficulty identifying cells that harbor...
8.
Favalli A, Favalli E, Gobbini A, Zagato E, Bombaci M, Maioli G, et al.
Front Immunol
. 2022 Jun;
13:873195.
PMID: 35757699
COVID-19 has proven to be particularly serious and life-threatening for patients presenting with pre-existing pathologies. Patients affected by rheumatic musculoskeletal disease (RMD) are likely to have impaired immune responses against...
9.
Butta G, Bozzi G, Gallo G, Copaloni G, Cordiglieri C, Crosti M, et al.
J Virol
. 2022 May;
96(10):e0037922.
PMID: 35499323
HIV integrates into the host genome, creating a viral reservoir of latently infected cells that persists despite effective antiretroviral treatment. CD4-positive (CD4) T cells are the main contributors to the...
10.
Francesconi O, Donnici L, Fragai M, Pesce E, Bombaci M, Fasciani A, et al.
iScience
. 2022 Apr;
25(5):104239.
PMID: 35434540
Developing strategies against the SARS-CoV-2 is currently a main research subject. SARS-CoV-2 infects host cells by binding to human ACE2 receptors. Both, virus and ACE2, are highly glycosylated, and exploiting...