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Allison W McClure

Explore the profile of Allison W McClure including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 168
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Recent Articles
1.
Henrikus S, Gross M, Willhoft O, Puhringer T, Lewis J, McClure A, et al.
Nat Struct Mol Biol . 2024 Sep; 31(11):1808. PMID: 39251823
No abstract available.
2.
Henrikus S, Gross M, Willhoft O, Puhringer T, Lewis J, McClure A, et al.
Nat Struct Mol Biol . 2024 May; 31(8):1265-1276. PMID: 38760633
To prevent detrimental chromosome re-replication, DNA loading of a double hexamer of the minichromosome maintenance (MCM) replicative helicase is temporally separated from DNA unwinding. Upon S-phase transition in yeast, DNA...
3.
McClure A, Canal B, Diffley J
DNA Repair (Amst) . 2022 Sep; 119:103393. PMID: 36108423
The DNA damage response (DDR) checkpoint is activated when DNA is damaged or when DNA replication forks stall. The DDR checkpoint plays a critical role in preserving the integrity of...
4.
McClure A, Diffley J
Elife . 2021 Aug; 10. PMID: 34387546
The Rad53 DNA checkpoint protein kinase plays multiple roles in the budding yeast cell response to DNA replication stress. Key amongst these is its enigmatic role in safeguarding DNA replication...
5.
Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, et al.
Biochem J . 2021 Jul; 478(13):2481-2497. PMID: 34198328
The COVID-19 pandemic has presented itself as one of the most critical public health challenges of the century, with SARS-CoV-2 being the third member of the Coronaviridae family to cause...
6.
Canal B, McClure A, Curran J, Wu M, Ulferts R, Weissmann F, et al.
Biochem J . 2021 Jul; 478(13):2445-2464. PMID: 34198326
SARS-CoV-2 is a coronavirus that emerged in 2019 and rapidly spread across the world causing a deadly pandemic with tremendous social and economic costs. Healthcare systems worldwide are under great...
7.
Canal B, Fujisawa R, McClure A, Deegan T, Wu M, Ulferts R, et al.
Biochem J . 2021 Jul; 478(13):2465-2479. PMID: 34198324
SARS-CoV-2 is responsible for COVID-19, a human disease that has caused over 2 million deaths, stretched health systems to near-breaking point and endangered economies of countries and families around the...
8.
McClure A, Jacobs K, Zyla T, Lew D
Mol Biol Cell . 2018 Oct; 29(26):3119-3127. PMID: 30355051
Studies of laboratory strains of have uncovered signaling pathways involved in mating, including information-processing strategies to optimize decisions to mate or to bud. However, lab strains are heterothallic (unable to...
9.
McClure A, Wu C, Johnson S, Lew D
Methods Mol Biol . 2016 Jun; 1407:13-23. PMID: 27271891
We describe methods for live-cell imaging of yeast cells that we have exploited to image yeast polarity establishment. As a rare event occurring on a fast time-scale, imaging polarization involves...
10.
McClure A, Minakova M, Dyer J, Zyla T, Elston T, Lew D
Dev Cell . 2015 Nov; 35(4):471-82. PMID: 26609960
Yeast cells track gradients of pheromones to locate mating partners. Intuition suggests that uniform distribution of pheromone receptors over the cell surface would yield optimal gradient sensing. However, yeast cells...