Michael Howell
Overview
Explore the profile of Michael Howell including associated specialties, affiliations and a list of published articles.
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Articles
145
Citations
6123
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Recent Articles
1.
Lu W, Zalmas L, Bailey C, Black J, Martinez-Ruiz C, Pich O, et al.
Nat Cell Biol
. 2024 Dec;
27(1):154-168.
PMID: 39738653
Chromosomal instability (CIN) is common in solid tumours and fuels evolutionary adaptation and poor prognosis by increasing intratumour heterogeneity. Systematic characterization of driver events in the TRACERx non-small-cell lung cancer...
2.
Clarke B, Ziff O, Tyzack G, Petric Howe M, Wang Y, Klein P, et al.
Mol Neurodegener
. 2024 Nov;
19(1):90.
PMID: 39593143
Background: Microglia play crucial roles in maintaining neuronal homeostasis but have been implicated in contributing to amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). However, the role of microglia in...
3.
Obika D, Kelly C, Ding N, Farrance C, Krause J, Mittal P, et al.
Nat Med
. 2024 Oct;
30(12):3417-3419.
PMID: 39438665
No abstract available.
4.
Postuma R, Vorasoot N, St Louis E, Pelletier A, Lim M, Elliott J, et al.
Neurol Neuroimmunol Neuroinflamm
. 2024 Sep;
11(6):e200311.
PMID: 39270144
Background And Objectives: Idiopathic/isolated REM sleep behavior disorder (iRBD) has been strongly linked to neurodegenerative synucleinopathies such as Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. However, there...
5.
Moreth D, Stevens-Cullinane L, Rees T, Muller V, Pasquier A, Song O, et al.
J Biol Inorg Chem
. 2024 Aug;
29(6):573-582.
PMID: 39198276
A series of biotin-functionalized transition metal complexes was prepared by iClick reaction from the corresponding azido complexes with a novel alkyne-functionalized biotin derivative ([Au(triazolato)(PPh)], [Pt(dpb)(triazolato)], [Pt(triazolato)(terpy)]PF, and [Ir(ppy)(triazolato)(terpy)]PF with dpb ...
6.
Reddy N, Berns M, Berns R, Olson H, Cui E, Miglis M, et al.
Sleep
. 2024 Aug;
47(11).
PMID: 39158284
No abstract available.
7.
OSullivan P, Aidarova A, Afonina I, Manils J, Thurston T, Instrell R, et al.
Biochem J
. 2024 Aug;
481(18):1143-1171.
PMID: 39145956
Rare mutations in CARD14 promote psoriasis by inducing CARD14-BCL10-MALT1 complexes that activate NF-κB and MAP kinases. Here, the downstream signalling mechanism of the highly penetrant CARD14E138A alteration is described. In...
8.
Bailey C, Sanderson T, Townsley H, Goldman J, Black J, Young G, et al.
Lancet
. 2023 Jun;
402(10395):21-24.
PMID: 37348521
No abstract available.
9.
Majidian M, Anderson J, Rock J, Ai R, Whitaker J, Howell M, et al.
J Drugs Dermatol
. 2023 May;
22(5):440-444.
PMID: 37133468
Importance: Actinic keratosis (AK) is a premalignant lesion that has a1% to 10% potential of progression to squamous cell carcinoma (SCC), but it is not possible to determine which lesions...
10.
Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer
Wu M, Shepherd S, Fendler A, Carr E, Au L, Harvey R, et al.
Cancer Cell
. 2023 Apr;
41(5):821-823.
PMID: 37116490
Wu et al. report that patients with hematologic malignancies have reduced immunity against SARS-CoV-2 Omicron subvariants and Sotrovimab retains neutralizing capacity against all tested Omicron subvariants.