Allison R Hickman
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Explore the profile of Allison R Hickman including associated specialties, affiliations and a list of published articles.
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11
Citations
38
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Recent Articles
1.
Gretarsson K, Abini-Agbomson S, Gloor S, Weinberg D, McCuiston J, Kumary V, et al.
Sci Adv
. 2024 Aug;
10(35):eadp0975.
PMID: 39196936
During tumor development, promoter CpG islands that are normally silenced by Polycomb repressive complexes (PRCs) become DNA-hypermethylated. The molecular mechanism by which de novo DNA methyltransferase(s) [DNMT(s)] catalyze CpG methylation...
2.
Gretarsson K, Abini-Agbomson S, Gloor S, Weinberg D, McCuiston J, Kumary V, et al.
bioRxiv
. 2024 Apr;
PMID: 38562823
During tumor development, promoter CpG islands (CGIs) that are normally silenced by Polycomb repressive complexes (PRCs) become DNA hypermethylated. The molecular mechanism by which DNA methyltransferase(s) catalyze CpG methylation at...
3.
Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone T, Hickman A, et al.
Cell
. 2024 Feb;
187(4):861-881.e32.
PMID: 38301646
Genomic instability can trigger cancer-intrinsic innate immune responses that promote tumor rejection. However, cancer cells often evade these responses by overexpressing immune checkpoint regulators, such as PD-L1. Here, we identify...
4.
Thomas J, Valencia-Sanchez M, Tamburri S, Gloor S, Rustichelli S, Godinez-Lopez V, et al.
Sci Adv
. 2023 Aug;
9(32):eadg9832.
PMID: 37556531
Histone H2A lysine 119 (H2AK119Ub) is monoubiquitinated by Polycomb repressive complex 1 and deubiquitinated by Polycomb repressive deubiquitinase complex (PR-DUB). PR-DUB cleaves H2AK119Ub to restrict focal H2AK119Ub at Polycomb target...
5.
Aguilar R, Khan L, Arslanovic N, Birmingham K, Kasliwal K, Posnikoff S, et al.
Res Sq
. 2023 Aug;
PMID: 37546815
Tardigrades are remarkable in their ability to survive extreme environments. The damage suppressor (Dsup) protein is thought responsible for their extreme resistance to reactive oxygen species (ROS) generated by irradiation....
6.
Thomas J, Valencia-Sanchez M, Tamburri S, Gloor S, Rustichelli S, Godinez-Lopez V, et al.
bioRxiv
. 2023 Mar;
PMID: 36865140
One Sentence Summary: We reveal the molecular mechanism of nucleosomal H2AK119Ub deubiquitination by human BAP1/ASXL1.
7.
Hickman A, Selee B, Pauly R, Husain B, Hang Y, Feltus F
J Autism Dev Disord
. 2022 Jun;
53(9):3595-3612.
PMID: 35739433
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder characterized by challenges in social communication as well as repetitive or restrictive behaviors. Many genetic associations with ASD have been identified,...
8.
Hickman A, Hang Y, Pauly R, Feltus F
G3 (Bethesda)
. 2021 Nov;
12(1).
PMID: 34791179
Uterine cancer is the fourth most common cancer among women, projected to affect 66,000 US women in 2021. Uterine cancer often arises in the inner lining of the uterus, known...
9.
Hang Y, Aburidi M, Husain B, Hickman A, Poehlman W, Feltus F
Sci Rep
. 2020 Oct;
10(1):17089.
PMID: 33051491
The human brain is a complex organ that consists of several regions each with a unique gene expression pattern. Our intent in this study was to construct a gene co-expression...
10.
Husain B, Hickman A, Hang Y, Shealy B, Sapra K, Feltus F
G3 (Bethesda)
. 2020 Jul;
10(9):2953-2963.
PMID: 32665353
Bigenic expression relationships are conventionally defined based on metrics such as Pearson or Spearman correlation that cannot typically detect latent, non-linear dependencies or require the relationship to be monotonic. Further,...