Alistair J Ingram
Overview
Explore the profile of Alistair J Ingram including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
32
Citations
1058
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Brimble K, Ingram A, Eikelboom J, Hart R
Postgrad Med
. 2013 Jan;
124(6):17-25.
PMID: 23322135
Atrial fibrillation (AF) is a common cardiac arrhythmia and is associated with an increased risk for thromboembolic stroke. Anticoagulant therapy has been shown to reduce the risk for ischemic stroke...
12.
Lovren F, Pan Y, Quan A, Singh K, Shukla P, Gupta N, et al.
Circulation
. 2012 Sep;
126(11 Suppl 1):S81-90.
PMID: 22965997
Background: MicroRNA are essential posttranscriptional modulators of gene expression implicated in various chronic diseases. Because microRNA-145 is highly expressed in vascular smooth muscle cells (VSMC) and regulates VSMC fate and...
13.
Hart R, Eikelboom J, Ingram A, Herzog C
Nat Rev Nephrol
. 2012 Jul;
8(10):569-78.
PMID: 22825670
Atrial fibrillation is an important cause of preventable, disabling stroke and is particularly frequent in patients with chronic kidney disease (CKD). Stage 3 CKD is an independent risk factor for...
14.
Lhotak S, Sood S, Brimble E, Carlisle R, Colgan S, Mazzetti A, et al.
Am J Physiol Renal Physiol
. 2012 May;
303(2):F266-78.
PMID: 22573382
Renal proximal tubule injury is induced by agents/conditions known to cause endoplasmic reticulum (ER) stress, including cyclosporine A (CsA), an immunosuppressant drug with nephrotoxic effects. However, the underlying mechanism by...
15.
Uttarwar L, Gao B, Ingram A, Krepinsky J
Am J Physiol Renal Physiol
. 2011 Oct;
302(3):F329-41.
PMID: 22031849
Glomerular matrix accumulation is a hallmark of diabetic nephropathy. Recent studies showed that overexpression of the transcription factor sterol-responsive element-binding protein (SREBP)-1 induces pathology reminiscent of diabetic nephropathy, and SREBP-1...
16.
He L, Fan C, Kapoor A, Ingram A, Rybak A, Austin R, et al.
Nat Commun
. 2011 May;
2:307.
PMID: 21556061
PTEN dephosphorylates the 3-position phosphate of phosphatidylinositol 3,4,5 triphosphate (PIP(3)), thereby inhibiting AKT activation. Although attenuation of PTEN function has a major role in tumourigenesis, the underlying mechanisms remain unclear....
17.
Wilkieson T, Ingram A, Crowther M, Soroka S, Nagai R, Jindal K, et al.
Clin J Am Soc Nephrol
. 2011 Apr;
6(5):1018-24.
PMID: 21493739
Background And Objectives: To determine whether warfarin prolongs the time to first mechanical-catheter failure. Design, Setting, Participants, & Measurements: This was a multicenter parallel-group randomized controlled trial with blinding of...
18.
Dickhout J, Lhotak S, Hilditch B, Basseri S, Colgan S, Lynn E, et al.
FASEB J
. 2010 Oct;
25(2):576-89.
PMID: 20966213
Endoplasmic reticulum (ER) stress causes macrophage cell death within advanced atherosclerotic lesions, thereby contributing to necrotic core formation and increasing the risk of atherothrombotic disease. However, unlike in advanced lesions,...
19.
Mechanical strain-induced RhoA activation requires NADPH oxidase-mediated ROS generation in caveolae
Zhang Y, Peng F, Gao B, Ingram A, Krepinsky J
Antioxid Redox Signal
. 2010 Apr;
13(7):959-73.
PMID: 20380579
Increased intraglomerular pressure leads to kidney fibrosis, and can be modeled by exposing glomerular mesangial cells (MC) to mechanical strain. We previously showed that RhoA mediates strain-induced matrix production. Here...
20.
Peng F, Zhang B, Ingram A, Gao B, Zhang Y, Krepinsky J
Cell Signal
. 2009 Sep;
22(1):34-40.
PMID: 19755152
Increased intraglomerular pressure is an important hemodynamic determinant of glomerulosclerosis, and can be modelled in vitro by exposing mesangial cells (MC) to cyclic mechanical stretch. We have previously shown that...