Alison M Bendele
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Explore the profile of Alison M Bendele including associated specialties, affiliations and a list of published articles.
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19
Citations
563
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Recent Articles
1.
Sulistio A, Mansfeld F, Reyes-Ortega F, DSouza A, Ng S, Birkett S, et al.
ACS Appl Bio Mater
. 2022 Jan;
2(7):2822-2832.
PMID: 35030816
The most common treatment for osteoarthritis is daily oral administration of a nonsteroidal anti-inflammatory drug such as diclofenac. This daily dosage regime is often associated with severe side effects. In...
2.
Bendele A, Neelagiri M, Neelagiri V, Sucholeiki I
Eur J Med Chem
. 2021 Jul;
224:113666.
PMID: 34245949
Osteoarthritis (OA) is a chronic disorder that causes damage to the cartilage and surrounding tissues and is characterized by pain, stiffness, and loss of function. Current treatments for OA primarily...
3.
Lakin B, Cooper B, Zakaria L, Grasso D, Wathier M, Bendele A, et al.
ACS Biomater Sci Eng
. 2019 Oct;
5(6):3060-3067.
PMID: 31608307
A poly(7-oxanorbornene-2-carboxylate) polymer containing pendent triethyleneglycol (TEG) chains of 2.8 MDa ("2.8M TEG") was synthesized and evaluated for long-term lubrication and wear reduction of ex vivo bovine cartilage as well...
4.
Wathier M, Lakin B, Cooper B, Bansal P, Bendele A, Entezari V, et al.
Biomaterials
. 2018 Aug;
182:13-20.
PMID: 30099277
Intra-articular injection of hyaluronic acid (HA) is used to treat osteoarthritis (OA) as a viscosupplement, yet it only provides short-term benefit because HA is cleaved by hyaluronidase and cleared out...
5.
Rosendahl M, Doherty D, Smith D, Bendele A, Cox G
Bioprocess Int
. 2018 Jun;
3(4):52-60.
PMID: 29899681
No abstract available.
6.
Lindstrom E, Rizoska B, Tunblad K, Edenius C, Bendele A, Maul D, et al.
J Transl Med
. 2018 Mar;
16(1):56.
PMID: 29523155
Background: MIV-711 is a highly potent and selective cathepsin K inhibitor. The current article summarizes the therapeutic effects of MIV-711 on joint pathology in rabbits subjected to anterior cruciate ligament...
7.
Emami A, Tepper J, Short B, Yaksh T, Bendele A, Ramani T, et al.
Int J Toxicol
. 2017 Dec;
37(1):4-27.
PMID: 29264927
As the need for nasal, ocular, spinal, and articular therapeutic compounds increases, toxicology assessments of drugs administered via these routes play an important role in human safety. This symposium outlined...
8.
Chandrasekhar S, Yu X, Harvey A, Oskins J, Lin C, Wang X, et al.
Pharmacol Res Perspect
. 2017 Jun;
5(3):e00316.
PMID: 28603634
Prostaglandin (PG) E is the key driver of inflammation associated with arthritic conditions. Inhibitors of PGE production (NSAIDs and Coxibs) are used to treat these conditions, but carry significant side...
9.
Wedekind K, Ruff K, Atwell C, Evans J, Bendele A
Mod Rheumatol
. 2016 Nov;
27(5):838-848.
PMID: 27846748
Objectives: This study was performed to evaluate the potential efficacy of natural eggshell membrane (NEM) in collagen-induced arthritic rats, a well-established rodent model of inflammation and rheumatoid arthritis. Methods: Rats...
10.
LaBranche T, Bendele A, Omura B, Gropp K, Hurst S, Bagi C, et al.
Ann Rheum Dis
. 2016 Jul;
76(1):295-302.
PMID: 27381034
Objective: To investigate whether the effects of nerve growth factor (NGF) inhibition with tanezumab on rats with medial meniscal tear (MMT) effectively model rapidly progressive osteoarthritis (RPOA) observed in clinical...