Aline Winkelmann
Overview
Explore the profile of Aline Winkelmann including associated specialties, affiliations and a list of published articles.
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14
Citations
251
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Recent Articles
1.
Kankowski S, Forstera B, Winkelmann A, Knauff P, Wanker E, You X, et al.
Front Mol Neurosci
. 2019 May;
12:103.
PMID: 31105523
[This corrects the article DOI: 10.3389/fnmol.2017.00439.].
2.
Kankowski S, Forstera B, Winkelmann A, Knauff P, Wanker E, You X, et al.
Front Mol Neurosci
. 2018 Jan;
10:439.
PMID: 29375302
C-to-U RNA editing of glycine receptors (GlyR) can play an important role in disease progression of temporal lobe epilepsy (TLE) as it may contribute in a neuron type-specific way to...
3.
Kumar A, Dejanovic B, Hetsch F, Semtner M, Fusca D, Arjune S, et al.
J Clin Invest
. 2017 Nov;
127(12):4365-4378.
PMID: 29106383
Molybdenum cofactor deficiency (MoCD) is an autosomal recessive inborn error of metabolism characterized by neurodegeneration and death in early childhood. The rapid and progressive neurodegeneration in MoCD presents a major...
4.
Raltschev C, Hetsch F, Winkelmann A, Meier J, Semtner M
J Biol Chem
. 2016 Jul;
291(34):18030-40.
PMID: 27382060
Glycine receptors are chloride-permeable, ligand-gated ion channels and contribute to the inhibition of neuronal firing in the central nervous system or to facilitation of neurotransmitter release if expressed at presynaptic...
5.
Caliskan G, Muller I, Semtner M, Winkelmann A, Raza A, Hollnagel J, et al.
Cereb Cortex
. 2016 Feb;
26(5):2325-2340.
PMID: 26908632
Parvalbumin-positive (PV) basket cells provide perisomatic inhibition in the cortex and hippocampus and control generation of memory-related network activity patterns, such as sharp wave ripples (SPW-R). Deterioration of this class...
6.
Winkelmann A, You X, Grunewald N, Haussler U, Krestel H, Haas C, et al.
PLoS One
. 2015 May;
10(5):e0125413.
PMID: 25955356
Establishment of phylogenetic relationships remains a challenging task because it is based on computational analysis of genomic hot spots that display species-specific sequence variations. Here, we identify a species-specific thymine-to-guanine...
7.
Kasim M, Benko E, Winkelmann A, Mrowka R, Staudacher J, Persson P, et al.
J Biol Chem
. 2014 Aug;
289(39):26973-26988.
PMID: 25124043
The basic helix-loop-helix transcription factor hASH1, encoded by the ASCL1 gene, plays an important role in neurogenesis and tumor development. Recent findings indicate that local oxygen tension is a critical...
8.
Forstera B, Dzaye O, Winkelmann A, Semtner M, Benedetti B, Markovic D, et al.
J Cell Sci
. 2014 Jul;
127(Pt 17):3687-98.
PMID: 24994934
The neuronal function of Cys-loop neurotransmitter receptors is established; however, their role in non-neuronal cells is poorly defined. As brain tumors are enriched in the neurotransmitter glycine, we studied the...
9.
Meier J, Meier J, Semtner M, Winkelmann A, Wolfart J
Front Cell Neurosci
. 2014 Jul;
8:164.
PMID: 24987332
Synaptic communication requires constant adjustments of pre- and postsynaptic efficacies. In addition to synaptic long term plasticity, the presynaptic machinery underlies homeostatic regulations which prevent out of range transmitter release....
10.
Winkelmann A, Maggio N, Eller J, Caliskan G, Semtner M, Haussler U, et al.
J Clin Invest
. 2014 Jan;
124(2):696-711.
PMID: 24430185
The mechanisms that regulate the strength of synaptic transmission and intrinsic neuronal excitability are well characterized; however, the mechanisms that promote disease-causing neural network dysfunction are poorly defined. We generated...