Alicia Alonso
Overview
Explore the profile of Alicia Alonso including associated specialties, affiliations and a list of published articles.
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158
Citations
4337
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Recent Articles
1.
McIntyre C, Grimont A, Park J, Meng Y, Sisso W, Seier K, et al.
Cancer Cell
. 2024 Aug;
42(9):1614-1629.e5.
PMID: 39214094
KRAS mutations in pancreatic ductal adenocarcinoma (PDAC) are suggested to vary in oncogenicity but the implications for human patients have not been explored in depth. We examined 1,360 consecutive PDAC...
2.
Ojeda P, Barjau M, Subiza J, Moreno A, Ojeda I, Solano E, et al.
Front Immunol
. 2024 Jul;
15:1431351.
PMID: 38989287
Background: Polymerized allergoids conjugated with mannan represent a novel approach of allergen immunotherapy targeting dendritic cells. In this study, we aimed to determine the optimal dose of mannan-allergoid conjugates derived...
3.
Ahyayauch H, Masserini M, Alonso A, Goni F
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928107
Aβ peptides are known to bind neural plasma membranes in a process leading to the deposit of Aβ-enriched plaques. These extracellular structures are characteristic of Alzheimer's disease, the major cause...
4.
Ballesteros U, Alonso A, Montes L, Etxaniz A
Autophagy
. 2024 May;
20(10):2349-2351.
PMID: 38818767
Among the MAP1LC3/LC3 subfamily of Atg8 proteins, LC3B and LC3C constitute the most and least studied members, respectively, LC3B being generally considered as an autophagosomal marker and a canonical representative...
5.
Ahyayauch H, Masserini M, Goni F, Alonso A
Biomolecules
. 2024 Mar;
14(3).
PMID: 38540718
The amyloidogenic Aβ peptides are widely considered as a pathogenic agent in Alzheimer's disease. Aβ(1-42) would form aggregates of amyloid fibrils on the neuron plasma membranes, thus perturbing neuronal functionality....
6.
Ballesteros U, Iriondo M, Varela Y, Goni F, Alonso A, Montes L, et al.
Int J Biol Macromol
. 2024 Feb;
262(Pt 1):129835.
PMID: 38302024
Autophagy is a catabolic process in which a double-membrane organelle, the autophagosome (AP), engulfs cellular components that will be degraded in the lysosomes. ATG8 protein family members participate at various...
7.
Franceschini G, Quaini O, Mizuno K, Orlando F, Ciani Y, Ku S, et al.
Cancer Discov
. 2024 Jan;
14(3):424-445.
PMID: 38197680
Significance: Neuroendocrine prostate cancer is an aggressive subtype of treatment-resistant prostate cancer. Early detection is important, but the diagnosis currently relies on metastatic biopsy. We describe the development and validation...
8.
Ballesteros U, Gonzalez-Ramirez E, de la Arada I, Sot J, Etxaniz A, Goni F, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38068893
-maleimide-derivatized phospholipids are often used to facilitate protein anchoring to membranes. In autophagy studies, this is applied to the covalent binding of Atg8, an autophagy protein, to a phosphatidylethanolamine (PE)...
9.
Varela Y, Iriondo M, Goni F, Alonso A, Montes L
Biochim Biophys Acta Mol Cell Biol Lipids
. 2023 Dec;
1869(2):159444.
PMID: 38056762
Specific membrane lipids play unique roles in (macro)autophagy. Those include phosphatidylethanolamine, to which LC3/GABARAP autophagy proteins become covalently bound in the process, or cardiolipin, an important effector in mitochondrial autophagy...
10.
Rudqvist N, Charpentier M, Lhuillier C, Wennerberg E, Spada S, Sheridan C, et al.
Nat Commun
. 2023 Aug;
14(1):5146.
PMID: 37620372
Radiation therapy (RT) increases tumor response to CTLA-4 inhibition (CTLA4i) in mice and in some patients, yet deep responses are rare. To identify rational combinations of immunotherapy to improve responses...