Ali Hachem
Overview
Explore the profile of Ali Hachem including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
63
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Recent Articles
1.
Hachem A, Convertino F, Batista T, Baptista F, Briassoulis D, Valera Martinez D, et al.
Sci Total Environ
. 2024 Jul;
946:174491.
PMID: 38969118
The escalating use of plastics in agriculture, driven by global population growth and increasing food demand, has concurrently led to a rise in Agricultural Plastic Waste (APW) production. Effective waste...
2.
Ayoub A, El-Achkar G, Ghayad S, Hariss L, Haidar R, Antar L, et al.
Int J Mol Sci
. 2023 Jun;
24(12).
PMID: 37373544
Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present...
3.
Velu D, Kantamneni L, Batool S, Hachem A
BMJ Case Rep
. 2022 Mar;
15(3).
PMID: 35264379
Haemophagocytic lymphohistiocytosis (HLH) is one of the rare haematological syndromes more commonly reported in infants/children than adults. This disease is known for its aggressive dysregulated immune response affecting the host...
4.
Paysant H, Hedir S, Justaud F, Weiswald L, El Dine A, Soulieman A, et al.
Org Biomol Chem
. 2021 Oct;
19(41):8968-8987.
PMID: 34596646
In the area of cancer research, the development of new and potent inhibitors of anti-apoptotic proteins is a very active and promising topic. The small molecule MIM1 has been reported...
5.
Kumar N, Kumar J, Hussain N, Gorelik L, Essandoh M, Whitson B, et al.
Semin Cardiothorac Vasc Anesth
. 2020 Dec;
25(3):173-184.
PMID: 33356967
Background: New or worsened mitral regurgitation (MR) is an uncommon yet serious complication after surgical aortic valve replacement (SAVR). While there have been numerous reports of its occurrence, there is...
6.
Ayoub A, Hariss L, El-Hachem N, El-Achkar G, Ghayad S, Dagher O, et al.
BMC Chem
. 2019 Nov;
13(1):124.
PMID: 31696161
Introduction: New fluorinated diaryl ethers and bisarylic ketones were designed and evaluated for their anti-inflammatory effects in primary macrophages. Methods: The synthesis of the designed molecules started from easily accessible...
7.
El Majzoub R, Fayyad-Kazan M, El Dine A, Makki R, Hamade E, Gree R, et al.
Genes Genomics
. 2019 Sep;
41(12):1431-1443.
PMID: 31541355
Background: Breast cancer, the most commonly diagnosed malignancy in women, accounts for the highest cancer-related deaths worldwide. Triple negative breast cancer (TNBC), lacking the expression of estrogen, progesterone and HER2...
8.
Bzeih T, Zhang K, Khalaf A, Hachem A, Alami M, Hamze A
J Org Chem
. 2018 Dec;
84(1):228-238.
PMID: 30523682
A one-pot Barluenga coupling between N-tosylhydrazones and nitro-benzyl bromide, followed by deoxygenation of ortho-nitrostyrenes, and subsequent cyclization has been developed, providing a new way to synthesize various C2-arylindoles. This method...
9.
Mouselmani R, Hachem A, Alaaeddine A, Metay E, Lemaire M
Org Biomol Chem
. 2018 Sep;
16(35):6600-6605.
PMID: 30175348
Herein we report the reduction of aromatic nitriles into aldehydes with calcium hypophosphite in the presence of base and nickel(ii) complex in a water/ethanol mixture. This catalytic system reduced efficiently...
10.
Bzeih T, Lamaa D, Frison G, Hachem A, Jaber N, Bignon J, et al.
Org Lett
. 2017 Dec;
19(24):6700-6703.
PMID: 29206470
A novel, sequential, palladium-catalyzed, cross-coupling reaction using N-tosylhydrazone and bromonitrobenzene derivatives followed by reductive cyclization has been developed. This transformation providing an efficient route to unexpected N-arylindole derivatives involves, in...