Ali H Brivanlou
Overview
Explore the profile of Ali H Brivanlou including associated specialties, affiliations and a list of published articles.
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106
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6458
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Recent Articles
21.
Haremaki T, Metzger J, Rito T, Zeeshan Ozair M, Etoc F, Brivanlou A
Nat Biotechnol
. 2019 Sep;
37(10):1198-1208.
PMID: 31501559
Harnessing the potential of human embryonic stem cells to mimic normal and aberrant development with standardized models is a pressing challenge. Here we use micropattern technology to recapitulate early human...
22.
Martyn I, Siggia E, Brivanlou A
Development
. 2019 Aug;
146(17).
PMID: 31427289
Although fate maps of early embryos exist for nearly all model organisms, a fate map of the gastrulating human embryo remains elusive. Here, we use human gastruloids to piece together...
23.
Simunovic M, Metzger J, Etoc F, Yoney A, Ruzo A, Martyn I, et al.
Nat Cell Biol
. 2019 Jul;
21(7):900-910.
PMID: 31263269
Breaking the anterior-posterior symmetry in mammals occurs at gastrulation. Much of the signalling network underlying this process has been elucidated in the mouse; however, there is no direct molecular evidence...
24.
Martyn I, Kanno T, Brivanlou A
Methods Mol Biol
. 2019 Jun;
2005:77-89.
PMID: 31175647
The combination of affordability, large size, and ease of access at almost every stage of development renders the chick an excellent model organism for studying vertebrate development. Not only is...
25.
Martyn I, Brivanlou A, Siggia E
Development
. 2019 Mar;
146(6).
PMID: 30814117
Long-range signaling by morphogens and their inhibitors define embryonic patterning yet quantitative data and models are rare, especially in humans. Here, we use a human embryonic stem cell micropattern system...
26.
Yoney A, Etoc F, Ruzo A, Carroll T, Metzger J, Martyn I, et al.
Elife
. 2018 Oct;
7.
PMID: 30311909
Self-organization of discrete fates in human gastruloids is mediated by a hierarchy of signaling pathways. How these pathways are integrated in time, and whether cells maintain a memory of their...
27.
Metzger J, Simunovic M, Brivanlou A
Curr Opin Genet Dev
. 2018 Jun;
52:86-91.
PMID: 29957587
Differentiation of embryonic stem cells in vitro is an important tool in dissecting and understanding the mechanisms that govern early embryologic development. In recent years, there has been considerable progress...
28.
hPSC Modeling Reveals that Fate Selection of Cortical Deep Projection Neurons Occurs in the Subplate
Zeeshan Ozair M, Kirst C, van den Berg B, Ruzo A, Rito T, Brivanlou A
Cell Stem Cell
. 2018 Jun;
23(1):60-73.e6.
PMID: 29937203
Cortical deep projection neurons (DPNs) are implicated in neurodevelopmental disorders. Although recent findings emphasize post-mitotic programs in projection neuron fate selection, the establishment of primate DPN identity during layer formation...
29.
30.
Ruzo A, Croft G, Metzger J, Galgoczi S, Gerber L, Pellegrini C, et al.
Development
. 2018 Jan;
145(2).
PMID: 29378824
Huntington's disease (HD) is a fatal neurodegenerative disease caused by expansion of CAG repeats in the Huntingtin gene (). Neither its pathogenic mechanisms nor the normal functions of HTT are...