Alfredo Ramirez
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Explore the profile of Alfredo Ramirez including associated specialties, affiliations and a list of published articles.
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201
Citations
7999
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Recent Articles
11.
Juarez-Cedillo T, Martinez-Rodriguez N, Juarez-Cedillo E, Ramirez A, Suerna-Hernandez A
Genes (Basel)
. 2024 Nov;
15(11).
PMID: 39596595
Background: Dementia causes the loss of functional independence, resulting in a decrease in the quality of life of those who suffer from it. Aims: This study aimed to investigate the...
12.
Wang X, Freiesleben S, Schneider L, Preis L, Priller J, Spruth E, et al.
Neurology
. 2024 Sep;
103(8):e209806.
PMID: 39303184
Background And Objectives: CSF biomarkers have immense diagnostic and prognostic potential for Alzheimer disease (AD). However, AD is still diagnosed relatively late in the disease process, sometimes even years after...
13.
Martino-Adami P, Chatterjee M, Kleineidam L, Weyerer S, Bickel H, Wiese B, et al.
Lancet Reg Health Eur
. 2024 Sep;
45:101030.
PMID: 39253733
Background: Blood-based biomarkers offer a promising, less invasive, and more cost-effective alternative for Alzheimer's disease screening compared to cerebrospinal fluid or imaging biomarkers. However, they have been extensively studied only...
14.
Beer S, Elmenhorst D, Bischof G, Ramirez A, Bauer A, Drzezga A
Neurobiol Aging
. 2024 Aug;
143:19-29.
PMID: 39208715
Aquaporin-4 (AQP4) is hypothesized to be a component of the glymphatic system, a pathway for removing brain interstitial solutes like amyloid-β (Aβ). Evidence exists that genetic variation of AQP4 impacts...
15.
Pan X, Chandrasekaran S, Woodside J, Riedel-Heller S, Scherer M, Wagner M, et al.
Anal Bioanal Chem
. 2024 Aug;
416(26):5711-5719.
PMID: 39160437
Queuosine (Q) is a hypermodified 7-deaza-guanosine nucleoside exclusively synthesized by bacteria. This micronutrient and its respective nucleobase form queuine (q) are salvaged by humans either from gut microflora or digested...
16.
Preis L, Villringer K, Brosseron F, Duzel E, Jessen F, Petzold G, et al.
Alzheimers Res Ther
. 2024 Jul;
16(1):172.
PMID: 39085945
Background: Blood-brain barrier (BBB) alterations may contribute to AD pathology through various mechanisms, including impaired amyloid-β (Aβ) clearance and neuroinflammation. Soluble platelet-derived growth factor receptor beta (sPDGFRβ) has emerged as...
17.
Ahmad S, Yang W, Orellana A, Frolich L, de Rojas I, Cano A, et al.
Alzheimers Res Ther
. 2024 Jul;
16(1):171.
PMID: 39080778
Background: Isoprostanes and prostaglandins are biomarkers for oxidative stress and inflammation. Their role in Alzheimer's disease (AD) pathophysiology is yet unknown. In the current study, we aim to identify the...
18.
Shao K, Hu X, Kleineidam L, Stark M, Altenstein S, Amthauer H, et al.
Alzheimers Dement
. 2024 Jul;
20(9):5926-5939.
PMID: 39072956
Introduction: Subjective cognitive decline (SCD) in amyloid-positive (Aβ+) individuals was proposed as a clinical indicator of Stage 2 in the Alzheimer's disease (AD) continuum, but this requires further validation across...
19.
Chatterjee M, Ozdemir S, Fritz C, Mobius W, Kleineidam L, Mandelkow E, et al.
Nat Med
. 2024 Jun;
30(6):1771-1783.
PMID: 38890531
Minimally invasive biomarkers are urgently needed to detect molecular pathology in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Here, we show that plasma extracellular vesicles (EVs) contain quantifiable amounts...
20.
Sampatakakis S, Mourtzi N, Charisis S, Kalligerou F, Mamalaki E, Ntanasi E, et al.
Biomedicines
. 2024 May;
12(5).
PMID: 38791015
The possible relationship between Subjective Cognitive Decline (SCD) and dementia needs further investigation. In the present study, we explored the association between specific biomarkers of Alzheimer's Disease (AD), amyloid-beta 42...