Alfred Boettcher
Overview
Explore the profile of Alfred Boettcher including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
21
Citations
526
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0
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Recent Articles
1.
Baumstark D, Kremer W, Boettcher A, Schreier C, Sander P, Schmitz G, et al.
J Lipid Res
. 2019 Jun;
60(9):1516-1534.
PMID: 31239285
NMR-based quantification of human lipoprotein (sub)classes is a powerful high-throughput method for medical diagnostics. We evaluated select proton NMR signals of serum lipoproteins for elucidating the physicochemical features and the...
2.
Orso E, Robenek H, Boettcher A, Wolf Z, Liebisch G, Kramer W, et al.
Cytometry A
. 2019 Apr;
95(8):869-884.
PMID: 30994973
Ezetimibe (EZE) and glucuronidated EZE (EZE-Glu) differentially target Niemann-Pick C1-like 1 (NPC1L1) and CD13 (aminopeptidase-N) to inhibit intestinal cholesterol absorption and cholesterol processing in other cells, although the precise molecular...
3.
Sigruener A, Wolfrum C, Boettcher A, Kopf T, Liebisch G, Orso E, et al.
PLoS One
. 2017 May;
12(5):e0178368.
PMID: 28542499
Background: Sequence variants near the human gene for P4-type ATPase, class V, type 10D (ATP10D) were shown to significantly associate with circulating hexosylceramide d18:1/16:0 and d18:1/24:1 levels, obesity, insulin resistance,...
4.
Pienimaeki-Roemer A, Konovalova T, Musri M, Sigruener A, Boettcher A, Meister G, et al.
Transfusion
. 2016 Dec;
57(1):144-156.
PMID: 28026009
Background: Platelets (PLTs) are derived from megakaryocytes during PLT shedding. Senescent or activated PLTs are expanded in vascular and neurological diseases and release PLT extracellular vesicles (PL-EVs). A systematic analysis...
5.
Heimerl S, Boettcher A, Kaul H, Liebisch G
Biochim Biophys Acta
. 2016 Apr;
1861(8 Pt A):681-7.
PMID: 27112638
Lipoprotein X (Lp-X) is an abnormal lipoprotein that may typically be formed in intra- and extrahepatic cholestasis and potentially interfere with lipid analysis in the routine lab. To gain insight...
6.
Hebel T, Eisinger K, Neumeier M, Rein-Fischboeck L, Pohl R, Meier E, et al.
Biochim Biophys Acta
. 2015 Jan;
1851(5):527-36.
PMID: 25625330
The syntrophins alpha (SNTA) and beta 2 (SNTB2) are molecular adaptor proteins shown to stabilize ABCA1, an essential regulator of HDL cholesterol. Furthermore, SNTB2 is involved in glucose stimulated insulin...
7.
Marko L, Paragh G, Ugocsai P, Boettcher A, Vogt T, Schling P, et al.
J Photochem Photobiol B
. 2012 Sep;
116:79-88.
PMID: 22982209
Many ATP binding cassette (ABC) transporters are important regulators of lipid homeostasis and have been implicated in keratinocyte lipid transport. Ultraviolet (UV) light exposure is a known epidermal stressor, which...
8.
Hambruch E, Miyazaki-Anzai S, Hahn U, Matysik S, Boettcher A, Perovic-Ottstadt S, et al.
J Pharmacol Exp Ther
. 2012 Aug;
343(3):556-67.
PMID: 22918042
Farnesoid X receptor (FXR), a bile acid-activated nuclear hormone receptor, plays an important role in the regulation of cholesterol and more specifically high-density lipoprotein (HDL) homeostasis. Activation of FXR is...
9.
Pienimaeki-Roemer A, Ruebsaamen K, Boettcher A, Orso E, Scherer M, Liebisch G, et al.
Transfusion
. 2012 Jul;
53(3):612-26.
PMID: 22804622
Background: Stored platelet concentrates (PLCs) for transfusion develop a platelet storage lesion (PSL), resulting in decreased platelet (PLT) viability and function. The processes leading to PSL have not been described...
10.
Ruebsaamen K, Liebisch G, Boettcher A, Schmitz G
Transfusion
. 2010 Feb;
50(8):1665-76.
PMID: 20158687
Background: A hallmark of platelet (PLT) storage lesion is the loss of PLT lipids. Due to technical limitations a detailed lipidomic analysis of plateletpheresis products during storage was so far...