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Alexis Vandenberghe

Explore the profile of Alexis Vandenberghe including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 368
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Recent Articles
1.
Manfroi B, Cuc B, Sokal A, Vandenberghe A, Temmam S, Attia M, et al.
Sci Transl Med . 2024 Sep; 16(765):eadl1997. PMID: 39292802
The development of the human immune system lasts for several years after birth. The impact of this maturation phase on the quality of adaptive immunity and the acquisition of immunological...
2.
Dejoux A, Zhu Q, Ganneau C, Goff O, Godon O, Lemaitre J, et al.
Sci Transl Med . 2024 Sep; 16(764):eado4463. PMID: 39259810
Neuromuscular blocking agents (NMBAs) relax skeletal muscles to facilitate surgeries and ease intubation but can lead to adverse reactions, including complications because of postoperative residual neuromuscular blockade (rNMB) and, in...
3.
Sokal A, Barba-Spaeth G, Hunault L, Fernandez I, Broketa M, Meola A, et al.
Immunity . 2023 Aug; 56(9):2137-2151.e7. PMID: 37543032
How infection by a viral variant showing antigenic drift impacts a preformed mature human memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC response up...
4.
Broketa M, Sokal A, Mor M, Canales-Herrerias P, Perima A, Meola A, et al.
JCI Insight . 2023 May; 8(13). PMID: 37252802
SARS-CoV-2 mRNA vaccination generates protective B cell responses targeting the SARS-CoV-2 spike glycoprotein. Whereas anti-spike memory B cell responses are long lasting, the anti-spike humoral antibody response progressively wanes, making...
5.
Canales-Herrerias P, Crickx E, Broketa M, Sokal A, Chenon G, Azzaoui I, et al.
J Clin Invest . 2022 May; 132(12). PMID: 35503254
The major therapeutic goal for immune thrombocytopenic purpura (ITP) is to restore normal platelet counts using drugs to promote platelet production or by interfering with mechanisms responsible for platelet destruction....
6.
Sokal A, Broketa M, Barba-Spaeth G, Meola A, Fernandez I, Fourati S, et al.
Immunity . 2022 Apr; 55(6):1096-1104.e4. PMID: 35483354
The SARS-CoV-2 Omicron variant can escape neutralization by vaccine-elicited and convalescent antibodies. Memory B cells (MBCs) represent another layer of protection against SARS-CoV-2, as they persist after infection and vaccination...
7.
Sokal A, Barba-Spaeth G, Fernandez I, Broketa M, Azzaoui I, de la Selle A, et al.
Immunity . 2021 Oct; 54(12):2893-2907.e5. PMID: 34614412
In addition to serum immunoglobulins, memory B cell (MBC) generation against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is another layer of immune protection, but the quality of MBC responses...
8.
Crickx E, Chappert P, Sokal A, Weller S, Azzaoui I, Vandenberghe A, et al.
Sci Transl Med . 2021 Apr; 13(589). PMID: 33853929
Rituximab (RTX), an antibody targeting CD20, is widely used as a first-line therapeutic strategy in B cell-mediated autoimmune diseases. However, a large proportion of patients either do not respond to...
9.
Sokal A, Chappert P, Barba-Spaeth G, Roeser A, Fourati S, Azzaoui I, et al.
Cell . 2021 Feb; 184(5):1201-1213.e14. PMID: 33571429
Memory B cells play a fundamental role in host defenses against viruses, but to date, their role has been relatively unsettled in the context of SARS-CoV-2. We report here a...
10.
Compain F, Vandenberghe A, Gominet M, Genel N, Lebeaux D, Ramahefasolo A, et al.
Emerg Microbes Infect . 2017 Jun; 6(6):e57. PMID: 28634354
No abstract available.