Alexey Zeifman
Overview
Explore the profile of Alexey Zeifman including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
57
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0
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Recent Articles
1.
Romanova J, Chikina E, Rydlovskaya A, Pohl W, Renner A, Zeifman A, et al.
Pulm Ther
. 2020 Oct;
6(2):351-369.
PMID: 33095411
Introduction: A significant number of patients with moderate asthma remain symptomatic despite treatment with inhaled corticosteroids (ICS). These patients do not yet meet the criteria for oral corticosteroids (OCS) and...
2.
Ballante F, Rudling A, Zeifman A, Luttens A, Vo D, Irwin J, et al.
J Med Chem
. 2019 Dec;
63(2):613-620.
PMID: 31846328
High-throughput screening has revealed dark chemical matter, a set of drug-like compounds that has never shown bioactivity despite being extensively assayed. If dark molecules are found active at a therapeutic...
3.
Jaiteh M, Zeifman A, Saarinen M, Svenningsson P, Brea J, Loza M, et al.
J Med Chem
. 2018 May;
61(12):5269-5278.
PMID: 29792714
Modulation of multiple biological targets with a single drug can lead to synergistic therapeutic effects and has been demonstrated to be essential for efficient treatment of CNS disorders. However, rational...
4.
Mannel B, Jaiteh M, Zeifman A, Randakova A, Moller D, Hubner H, et al.
ACS Chem Biol
. 2017 Aug;
12(10):2652-2661.
PMID: 28846380
Functionally selective ligands stabilize conformations of G protein-coupled receptors (GPCRs) that induce a preference for signaling via a subset of the intracellular pathways activated by the endogenous agonists. The possibility...
5.
Chelysheva E, Turkina A, Polushkina E, Shmakov R, Zeifman A, Aleshin S, et al.
Leuk Lymphoma
. 2017 Jul;
59(3):733-738.
PMID: 28703026
Both favorable pregnancy outcomes and fetal abnormalities have been associated with the use of tyrosine kinase inhibitors (TKIs) during pregnancy. The placental transfer of TKIs in humans is poorly understood....