Alexei Poliakov
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Explore the profile of Alexei Poliakov including associated specialties, affiliations and a list of published articles.
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12
Citations
471
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Recent Articles
1.
Taylor H, Khuong A, Wu Z, Xu Q, Morley R, Gregory L, et al.
J R Soc Interface
. 2017 Jul;
14(132).
PMID: 28747399
Eph receptor and ephrin signalling has a major role in cell segregation and border formation, and may act through regulation of cell adhesion, repulsion or tension. To elucidate roles of...
2.
Jorgensen C, Poliakov A
Methods Mol Biol
. 2013 Aug;
1066:1-16.
PMID: 23955729
Large-scale biochemical analysis of cell-specific signaling can be interrogated in cocultures of Eph receptor- and ephrin-expressing cells by combining proteomics analysis with cell-specific metabolic labeling. In this chapter, we describe...
3.
Taylor W, Morley R, Krasavin A, Gregory L, Wilkinson D, Poliakov A
PLoS One
. 2012 Sep;
7(8):e43226.
PMID: 22952652
From simulations that begin with a random mix of two cell types, we monitor progress towards segregation driven by contact-mediated linkage of model cells, which is equivalent to the cell-cell...
4.
Kapustin A, Stepanova V, Aniol N, Cines D, Poliakov A, Yarovoi S, et al.
Biochem J
. 2012 Jan;
443(2):491-503.
PMID: 22280367
uPA (urokinase-type plasminogen activator) stimulates cell migration through multiple pathways, including formation of plasmin and extracellular metalloproteinases, and binding to the uPAR (uPA receptor; also known as CD87), integrins and...
5.
Taylor W, Katsimitsoulia Z, Poliakov A
J Bioinform Comput Biol
. 2011 Feb;
9(1):91-110.
PMID: 21328708
A mechanical model of cell motion was developed that reproduced the behaviour of cells in 2-dimensional culture. Cell adhesion was modelled with inter-cellular cross-links that attached for different times giving...
6.
Chibalina M, Poliakov A, Kendrick-Jones J, Buss F
Traffic
. 2010 Jul;
11(10):1290-303.
PMID: 20604900
The polarized trafficking of membrane proteins into the leading edge of the cell is an integral requirement for cell migration. Myosin VI and its interacting protein optineurin have previously been...
7.
Sobieszczuk D, Poliakov A, Xu Q, Wilkinson D
Genes Dev
. 2010 Jan;
24(2):206-18.
PMID: 20080956
Neuronal differentiation is regulated by proneural genes that promote neurogenesis and inhibitory mechanisms that maintain progenitors. This raises the question of how the up-regulation of proneural genes required to initiate...
8.
Jorgensen C, Sherman A, Chen G, Pasculescu A, Poliakov A, Hsiung M, et al.
Science
. 2009 Dec;
326(5959):1502-9.
PMID: 20007894
Cells have self-organizing properties that control their behavior in complex tissues. Contact between cells expressing either B-type Eph receptors or their transmembrane ephrin ligands initiates bidirectional signals that regulate cell...
9.
Poliakov A, Cotrina M, Pasini A, Wilkinson D
J Cell Biol
. 2008 Dec;
183(5):933-47.
PMID: 19047466
In this study, we investigated whether the ability of Eph receptor signaling to mediate cell repulsion is antagonized by fibroblast growth factor receptor (FGFR) activation that can promote cell invasion....
10.
Rubina K, Kalinina N, Potekhina A, Efimenko A, Semina E, Poliakov A, et al.
Angiogenesis
. 2007 May;
10(3):183-95.
PMID: 17486418
Our previous studies have revealed the abundant expression of T-cadherin--a glycosylphosphatidylinositol (GPI)-anchored member of cadherin superfamily--in endothelial and mural cells in the heart and vasculature. The upregulation of T-cadherin in...