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Alexandros Papanikolaou

Explore the profile of Alexandros Papanikolaou including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 368
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Recent Articles
1.
Dobo K, Kenyon M, Dirat O, Engel M, Fleetwood A, Martin M, et al.
Chem Res Toxicol . 2022 Feb; 35(3):475-489. PMID: 35212515
The potential for -nitrosamine impurities in pharmaceutical products presents a challenge for the quality management of medicinal products. -Nitrosamines are considered cohort-of-concern compounds due to the potent carcinogenicity of many...
2.
Papanikolaou A, Panitsa M
Biodivers Data J . 2020 Jan; 8:e48704. PMID: 31997895
Lake Kastoria is one of the potentially "ancient" Balkan lakes that has a great environmental importance and ecological value, attracts high touristic interest and is under various anthropogenic pressures. It...
3.
Sarika M, Papanikolaou A, Yannitsaros A, Chitos T, Panitsa M
Biodivers Data J . 2019 Sep; 7:e37023. PMID: 31523160
Lake Pamvotis is one of the Balkan "ancient" lakes, a Quaternary refugium of great environmental importance and ecological value, that is under various anthropogenic pressures. It belongs to a Natura...
4.
Radi Z, Vogel W, Bartholomew P, Koza-Taylor P, Papanikolaou A, Wisialowski T, et al.
Regul Toxicol Pharmacol . 2017 Oct; 91:93-102. PMID: 29074274
Tofacitinib is an oral JAK inhibitor for the treatment of rheumatoid arthritis. In the 2-year carcinogenicity study with tofacitinib, increased incidence of hibernoma (a neoplasm of brown adipose tissue [BAT])...
5.
Dermitzakis E, Kimiskidis V, Lazaridis G, Alexopoulou Z, Timotheadou E, Papanikolaou A, et al.
BMC Neurol . 2016 Oct; 16(1):190. PMID: 27716097
Background: Paclitaxel-based regimens are frequently associated with the development of peripheral neuropathy. The autonomous nervous system (ANS) effects, however, of this chemotherapeutic agent remain unexplored. Methods: We investigated a group...
6.
Casimiro M, Di Sante G, Crosariol M, Loro E, Dampier W, Ertel A, et al.
Oncotarget . 2015 May; 6(11):8525-38. PMID: 25940700
Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics. Currently, pharmaceutical initiatives...
7.
Brodney M, Johnson D, Sawant-Basak A, Coffman K, Drummond E, Hudson E, et al.
J Med Chem . 2012 Sep; 55(21):9240-54. PMID: 22974325
The cognitive impairments observed in Alzheimer's disease (AD) are in part a consequence of reduced acetylcholine (ACh) levels resulting from a loss of cholinergic neurons. Preclinically, serotonin 4 receptor (5-HT(4))...
8.
Shirai N, Papanikolaou A, Perry R
Toxicol Pathol . 2012 Apr; 40(5):819-22. PMID: 22467626
The present article describes an unusual proliferative islet finding observed incidentally in a young male Wistar rat in a 2-week toxicity study. Histologically, the islet lesion was characterized by diffuse...
9.
Aravantinos G, Fountzilas G, Bamias A, Grimani I, Rizos S, Kalofonos H, et al.
Eur J Cancer . 2008 Aug; 44(15):2169-77. PMID: 18691879
Introduction: The combination of Carboplatin and Paclitaxel is considered the standard of care as initial chemotherapy for Advanced Ovarian Cancer (AOC). We compared this regimen with the combination of Cisplatin,...
10.
Sakamaki T, Casimiro M, Ju X, Quong A, Katiyar S, Liu M, et al.
Mol Cell Biol . 2006 Jul; 26(14):5449-69. PMID: 16809779
The cyclin D1 gene encodes a regulatory subunit of the holoenzyme that phosphorylates and inactivates the pRb tumor suppressor to promote nuclear DNA synthesis. cyclin D1 is overexpressed in human...