Alexandre P Marand
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Explore the profile of Alexandre P Marand including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Marand A
bioRxiv
. 2023 Jan;
PMID: 36711646
The blueprints to development, response to the environment, and cellular function are largely the manifestation of distinct gene expression programs controlled by the spatiotemporal activity of -regulatory elements. Although biochemical...
12.
Marand A, Eveland A, Kaufmann K, Springer N
Annu Rev Plant Biol
. 2023 Jan;
74:111-137.
PMID: 36608347
Regulatory elements encode the genomic blueprints that ensure the proper spatiotemporal patterning of gene expression necessary for appropriate development and responses to the environment. Accumulating evidence implicates changes to gene...
13.
Wrightsman T, Marand A, Crisp P, Springer N, Buckler E
Plant Genome
. 2022 Aug;
15(3):e20249.
PMID: 35924336
Accessible chromatin regions are critical components of gene regulation but modeling them directly from sequence remains challenging, especially within plants, whose mechanisms of chromatin remodeling are less understood than in...
14.
Tu X, Marand A, Schmitz R, Zhong S
Plant Commun
. 2022 May;
3(4):100308.
PMID: 35605196
Understanding how cis-regulatory elements facilitate gene expression is a key question in biology. Recent advances in single-cell genomics have led to the discovery of cell-specific chromatin landscapes that underlie transcription...
15.
Noshay J, Liang Z, Zhou P, Crisp P, Marand A, Hirsch C, et al.
G3 (Bethesda)
. 2021 Dec;
11(8).
PMID: 34849810
Accessible chromatin and unmethylated DNA are associated with many genes and cis-regulatory elements. Attempts to understand natural variation for accessible chromatin regions (ACRs) and unmethylated regions (UMRs) often rely upon...
16.
Schmitz R, Marand A, Zhang X, Mosher R, Turck F, Chen X, et al.
Plant Cell
. 2021 Oct;
34(1):503-513.
PMID: 34648025
Epigenomics is the study of molecular signatures associated with discrete regions within genomes, many of which are important for a wide range of nuclear processes. The ability to profile the...
17.
Mendieta J, Marand A, Ricci W, Zhang X, Schmitz R
G3 (Bethesda)
. 2021 Sep;
11(10).
PMID: 34568920
Accurate genome annotations are essential to modern biology; however, they remain challenging to produce. Variation in gene structure and expression across species, as well as within an organism, make correctly...
18.
Marand A, Zhang X, Nelson J, Braga Dos Reis P, Schmitz R
STAR Protoc
. 2021 Aug;
2(3):100737.
PMID: 34430912
Coupling assay for transposase-accessible chromatin sequencing (ATAC-seq) with microfluidic separation and cellular barcoding has emerged as a powerful approach to investigate chromatin accessibility of individual cells. Here, we define a...
19.
Marand A, Schmitz R
Curr Opin Plant Biol
. 2021 Aug;
65:102094.
PMID: 34390932
Plant tissues and organs are composed of functionally discrete cell types that are all defined by the same genome sequence. Cell-type variation in part arises from differential accessibility of cis-regulatory...
20.
Hufford M, Seetharam A, Woodhouse M, Chougule K, Ou S, Liu J, et al.
Science
. 2021 Aug;
373(6555):655-662.
PMID: 34353948
We report de novo genome assemblies, transcriptomes, annotations, and methylomes for the 26 inbreds that serve as the founders for the maize nested association mapping population. The number of pan-genes...