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Alexandre P Marand

Explore the profile of Alexandre P Marand including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1198
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Recent Articles
1.
Zhang X, Luo Z, Marand A, Yan H, Jang H, Bang S, et al.
Cell . 2025 Jan; 188(2):550-567.e19. PMID: 39742806
Cis-regulatory elements (CREs) precisely control spatiotemporal gene expression in cells. Using a spatially resolved single-cell atlas of gene expression with chromatin accessibility across ten soybean tissues, we identified 103 distinct...
2.
Schlegel L, Bhardwaj R, Shahryary Y, Demirturk D, Marand A, Schmitz R, et al.
NAR Genom Bioinform . 2024 Sep; 6(3):lqae123. PMID: 39318505
Gene regulation in eukaryotes is partly shaped by the 3D organization of chromatin within the cell nucleus. Distal interactions between -regulatory elements and their target genes are widespread, and many...
3.
Mendieta J, Tu X, Jiang D, Yan H, Zhang X, Marand A, et al.
Proc Natl Acad Sci U S A . 2024 Sep; 121(40):e2402781121. PMID: 39312655
While considerable knowledge exists about the enzymes pivotal for C photosynthesis, much less is known about the regulation important for specifying their expression in distinct cell types. Here, we use...
4.
Zhang X, Luo Z, Marand A, Yan H, Jang H, Bang S, et al.
bioRxiv . 2024 Jul; PMID: 39005400
-regulatory elements (CREs) precisely control spatiotemporal gene expression in cells. Using a spatially resolved single-cell atlas of gene expression with chromatin accessibility across ten soybean tissues, we identified 103 distinct...
5.
Zhang X, Marand A, Yan H, Schmitz R
Genome Biol . 2024 Apr; 25(1):90. PMID: 38589969
Single-cell ATAC-seq has emerged as a powerful approach for revealing candidate cis-regulatory elements genome-wide at cell-type resolution. However, current single-cell methods suffer from limited throughput and high costs. Here, we...
6.
Minnoye L, Marinov G, Krausgruber T, Pan L, Marand A, Secchia S, et al.
Nat Rev Methods Primers . 2024 Feb; 1. PMID: 38410680
Chromatin accessibility, or the physical access to chromatinized DNA, is a widely studied characteristic of the eukaryotic genome. As active regulatory DNA elements are generally 'accessible', the genome-wide profiling of...
7.
Mendieta J, Tu X, Jiang D, Yan H, Zhang X, Marand A, et al.
bioRxiv . 2024 Feb; PMID: 38405933
While considerable knowledge exists about the enzymes pivotal for C photosynthesis, much less is known about the -regulation important for specifying their expression in distinct cell types. Here, we use...
8.
Yan H, Mendieta J, Zhang X, Marand A, Liang Y, Luo Z, et al.
bioRxiv . 2024 Jan; PMID: 38260561
Cis-regulatory elements (CREs) are critical in regulating gene expression, and yet understanding of CRE evolution remains challenging. Here, we constructed a comprehensive single-cell atlas of chromatin accessibility in Oryza sativa,...
9.
Zhang X, Marand A, Yan H, Schmitz R
bioRxiv . 2023 Oct; PMID: 37786710
Single-cell ATAC-seq has emerged as a powerful approach for revealing candidate -regulatory elements genome-wide at cell-type resolution. However, current single-cell methods suffer from limited throughput and high costs. Here, we...
10.
Minow M, Marand A, Schmitz R
Annu Rev Genet . 2023 Aug; 57:297-319. PMID: 37562412
The ease and throughput of single-cell genomics have steadily improved, and its current trajectory suggests that surveying single-cell populations will become routine. We discuss the merger of quantitative genetics with...