Alexandra Stege
Overview
Explore the profile of Alexandra Stege including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
156
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hannemann J, Zink A, Mileva Y, Balfanz P, Dahl E, Volland S, et al.
Sci Rep
. 2024 Jul;
14(1):15739.
PMID: 38977837
Mortality of patients hospitalized with COVID-19 has remained high during the consecutive SARS-CoV-2 pandemic waves. Early discrimination of patients at high mortality risk is crucial for optimal patient care. Symmetric...
2.
Grove J, Stephens C, Lucena M, Andrade R, Weber S, Gerbes A, et al.
Diagn Progn Res
. 2023 Sep;
7(1):18.
PMID: 37697410
A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative's...
3.
Schoisswohl S, Langguth B, Schecklmann M, Bernal-Robledano A, Boecking B, Cederroth C, et al.
Trials
. 2021 Dec;
22(1):875.
PMID: 34863270
Background: Tinnitus represents a relatively common condition in the global population accompanied by various comorbidities and severe burden in many cases. Nevertheless, there is currently no general treatment or cure,...
4.
Schlee W, Schoisswohl S, Staudinger S, Schiller A, Lehner A, Langguth B, et al.
Prog Brain Res
. 2021 Feb;
260:441-451.
PMID: 33637231
Tinnitus is the perception of a phantom sound and the patient's reaction to it. Although much progress has been made, tinnitus remains a scientific and clinical enigma of high prevalence...
5.
Stege A, Kruhn A, Lage H
Methods Mol Biol
. 2009 Dec;
596:447-65.
PMID: 19949936
The ATP-binding cassette (ABC)-transporter P-glycoprotein (Pgp, also known as ABCB1) is the best characterized factor involved in multidrug resistance (MDR) of cancer cells. Pgp, which is encoded by the MDR1...
6.
Stein U, Walther W, Stege A, Kaszubiak A, Fichtner I, Lage H
Mol Ther
. 2007 Sep;
16(1):178-86.
PMID: 17878902
Triggering the RNA interference (RNAi) pathway by inducing the expression of short hairpin RNA (shRNA) molecules has become a promising tool for efficient silencing of a given gene in gene...
7.
Priebsch A, Rompe F, Tonnies H, Kowalski P, Surowiak P, Stege A, et al.
Oligonucleotides
. 2006 Sep;
16(3):263-74.
PMID: 16978089
In the chemotherapeutic treatment of patients with disseminated neoplasms, multidrug resistance (MDR) is a major obstacle. ABCG2 (BCRP/MXR), a member of the superfamily of adenosine triphosphate-binding cassette (ABC) transporters, was...
8.
Materna V, Stege A, Surowiak P, Priebsch A, Lage H
Biochem Biophys Res Commun
. 2006 Aug;
348(1):153-7.
PMID: 16876126
The adenosine triphosphate binding cassette (ABC)-transporter ABCC2 (MRP2/cMOAT) can mediate resistance against the commonly used anticancer drugs cisplatin and paclitaxel. To overcome the ABCC2-depending drug resistance, two specific anti-ABCC2 small...
9.
Stege A, Priebsch A, Nieth C, Lage H
Cancer Gene Ther
. 2004 Sep;
11(11):699-706.
PMID: 15375376
Multidrug resistance (MDR) is the major cause of failure of effective chemotherapeutic treatment of disseminated neoplasms. The "classical" MDR phenotype of human malignancies is mediated by drug extrusion by the...
10.
Wichert A, Stege A, Midorikawa Y, Holm P, Lage H
Oncogene
. 2003 Dec;
23(4):945-55.
PMID: 14661052
Elevated expression of the heparan sulphate proteoglycan glypican-3 (GPC3) was found on mRNA and protein levels in the atypical multidrug-resistant gastric carcinoma cell line EPG85-257RNOV, which was established by in...