Alexandra K Marr
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Explore the profile of Alexandra K Marr including associated specialties, affiliations and a list of published articles.
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22
Citations
901
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Recent Articles
11.
Leishmania donovani infection causes distinct epigenetic DNA methylation changes in host macrophages
Marr A, MacIsaac J, Jiang R, Airo A, Kobor M, McMaster W
PLoS Pathog
. 2014 Oct;
10(10):e1004419.
PMID: 25299267
Infection of macrophages by the intracellular protozoan Leishmania leads to down-regulation of a number of macrophage innate host defense mechanisms, thereby allowing parasite survival and replication. The underlying molecular mechanisms...
12.
Wang X, Marr A, Breitkopf T, Leung G, Hao J, Wang E, et al.
J Invest Dermatol
. 2013 Sep;
134(3):736-745.
PMID: 24005055
The immune privilege (IP) of hair follicles (HFs) has been well established in previous studies. However, whether cultured HF cells still exhibit IP properties, the individual factors involved in this...
13.
Lynn M, Marr A, McMaster W
J Proteomics
. 2013 Mar;
82:179-92.
PMID: 23466312
Biological Significance: Leishmania, protozoan parasites of the Trypanosomatidae family, are the causative agents of leishmaniasis that represents a major public health concern affecting more than 20million people globally Membrane associated...
14.
Marr A, McGwire B, McMaster W
Future Microbiol
. 2012 Sep;
7(9):1047-59.
PMID: 22953706
Leishmaniasis is one of the major neglected tropical diseases of the world. It is present in 88 countries with an estimated number of 500,000 cases of visceral leishmaniasis and 1.5...
15.
Lynn M, Kindrachuk J, Marr A, Jenssen H, Pante N, Elliott M, et al.
PLoS Negl Trop Dis
. 2011 Jun;
5(5):e1141.
PMID: 21655347
Background: Protozoan parasites, such as Leishmania, still pose an enormous public health problem in many countries throughout the world. Current measures are outdated and have some associated drug resistance, prompting...
16.
Nuclear envelope disruption involving host caspases plays a role in the parvovirus replication cycle
Cohen S, Marr A, Garcin P, Pante N
J Virol
. 2011 Mar;
85(10):4863-74.
PMID: 21367902
Parvoviruses are small, nonenveloped, single-stranded DNA viruses which replicate in the nucleus of the host cell. We have previously found that early during infection the parvovirus minute virus of mice...
17.
Schurek K, Marr A, Taylor P, Wiegand I, Semenec L, Khaira B, et al.
Antimicrob Agents Chemother
. 2008 Oct;
52(12):4213-9.
PMID: 18824604
Pseudomonas aeruginosa strains isolated from patients with persistent lung infections and cystic fibrosis have been found to gradually develop aminoglycoside resistance over time. The aim of this study was to...
18.
Wiegand I, Marr A, Breidenstein E, Schurek K, Taylor P, Hancock R
Antimicrob Agents Chemother
. 2008 Jul;
52(10):3810-3.
PMID: 18663021
Screening of the PA14 genomic transposon mutant library for resistance to ceftazidime, tobramycin, and ciprofloxacin led to the discovery of several mutants that appeared in more than one screen. Testing...
19.
Marr A, Overhage J, Bains M, Hancock R
Microbiology (Reading)
. 2007 Jan;
153(Pt 2):474-482.
PMID: 17259618
Pseudomonas aeruginosa is an important nosocomial opportunistic human pathogen and a major cause of chronic lung infections in individuals with cystic fibrosis. Serious infections by this organism are often treated...
20.
Overhage J, Lewenza S, Marr A, Hancock R
J Bacteriol
. 2006 Dec;
189(5):2164-9.
PMID: 17158671
During a screening of a mini-Tn5-luxCDABE transposon mutant library of Pseudomonas aeruginosa PAO1 for alterations in swarming motility, 36 mutants were identified with Tn5 insertions in genes for the synthesis...