Alexandra E Paharik
Overview
Explore the profile of Alexandra E Paharik including associated specialties, affiliations and a list of published articles.
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11
Citations
644
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Recent Articles
1.
Worby C, Schreiber 4th H, Straub T, van Dijk L, Bronson R, Olson B, et al.
Nat Microbiol
. 2022 May;
7(5):630-639.
PMID: 35505248
Recurrent urinary tract infections (rUTIs) are a major health burden worldwide, with history of infection being a significant risk factor. While the gut is a known reservoir for uropathogenic bacteria,...
2.
Paharik A, Schreiber 4th H, Spaulding C, Dodson K, Hultgren S
Genome Med
. 2017 Dec;
9(1):110.
PMID: 29241446
Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial microbial communities...
3.
Paharik A, Parlet C, Chung N, Todd D, Rodriguez E, Van Dyke M, et al.
Cell Host Microbe
. 2017 Dec;
22(6):746-756.e5.
PMID: 29199097
Coagulase-negative staphylococci (CoNS) and Staphylococcus aureus are part of the natural flora of humans and other mammals. We found that spent media from the CoNS species Staphylococcus caprae can inhibit...
4.
Nicholson T, Brockmeier S, Sukumar N, Paharik A, Lister J, Horswill A, et al.
Infect Immun
. 2017 Jun;
85(8).
PMID: 28559403
is pervasive in swine populations and plays multiple roles in respiratory disease. Additionally, is capable of establishing long-term or chronic infections in swine. Bacterial biofilms are increasingly recognized as important...
5.
Paharik A, Kotasinska M, Both A, Hoang T, Buttner H, Roy P, et al.
Mol Microbiol
. 2016 Dec;
103(5):860-874.
PMID: 27997732
The otherwise harmless skin inhabitant Staphylococcus epidermidis is a major cause of healthcare-associated medical device infections. The species' selective pathogenic potential depends on its production of surface adherent biofilms. The...
6.
Paharik A, Salgado-Pabon W, Meyerholz D, White M, Schlievert P, Horswill A
mSphere
. 2016 Oct;
1(5).
PMID: 27747296
The Spl proteases are a group of six serine proteases that are encoded on the νSaβ pathogenicity island and are unique to . Despite their interesting biochemistry, their biological substrates...
7.
Paharik A, Horswill A
Microbiol Spectr
. 2016 May;
4(2).
PMID: 27227309
The staphylococci comprise a diverse genus of Gram-positive, nonmotile commensal organisms that inhabit the skin and mucous membranes of humans and other mammals. In general, staphylococci are benign members of...
8.
Yang T, Tal-Gan Y, Paharik A, Horswill A, Blackwell H
ACS Chem Biol
. 2016 May;
11(7):1982-91.
PMID: 27159024
Staphylococcus epidermidis is frequently implicated in human infections associated with indwelling medical devices due to its ubiquity in the skin flora and formation of robust biofilms. The accessory gene regulator...
9.
Kiedrowski M, Paharik A, Ackermann L, Shelton A, Singh S, Starner T, et al.
Cell Microbiol
. 2015 Nov;
18(5):720-32.
PMID: 26566259
Staphylococcus aureus is a bacterial pathogen responsible for a wide range of diseases and is also a human commensal colonizing the upper respiratory tract. Strains belonging to the clonal complex...
10.
Schaeffer C, Woods K, Longo G, Kiedrowski M, Paharik A, Buttner H, et al.
Infect Immun
. 2014 Oct;
83(1):214-26.
PMID: 25332125
Biofilm formation is the primary virulence factor of Staphylococcus epidermidis. S. epidermidis biofilms preferentially form on abiotic surfaces and may contain multiple matrix components, including proteins such as accumulation-associated protein...