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Alexandra E Livanos

Explore the profile of Alexandra E Livanos including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 475
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Recent Articles
1.
Bloemen H, Livanos A, Martins A, Dean R, Bravo A, Bourgonje A, et al.
Clin Gastroenterol Hepatol . 2024 Nov; PMID: 39490950
Background & Aims: Anti-integrin αvβ6 autoantibodies (anti-αvβ6) are found in more than 50% of individuals with ulcerative colitis (UC). We aimed to determine the prevalence of anti-αvβ6 in patients with...
2.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
Sci Immunol . 2024 Oct; 9(100):eado0090. PMID: 39454027
Gastrointestinal (GI) B cells and plasma cells (PCs) are critical to mucosal homeostasis and the host response to HIV-1 infection. Here, high-resolution mapping of human B cells and PCs sampled...
3.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
bioRxiv . 2024 Jun; PMID: 38826293
One Sentence Summary: Intestinal germinal center B cell reduction in HIV-1 infection linked to reduced IgA plasma cells and systemic inflammation.
4.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski R, Verstockt B, Livanos A, et al.
Sci Immunol . 2024 Apr; 9(94):eadg7549. PMID: 38640252
Vedolizumab (VDZ) is a first-line treatment in ulcerative colitis (UC) that targets the α4β7- mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) axis. To determine the mechanisms of action of...
5.
Law C, Peraza J, Viera Feliciano N, Ungaro R, Cheesman K, Colombel J, et al.
Dig Dis Sci . 2023 Oct; 68(12):4327-4330. PMID: 37831398
No abstract available.
6.
Jha D, Al-Taie Z, Krek A, Toghi Eshghi S, Fantou A, Laurent T, et al.
bioRxiv . 2023 Jun; PMID: 37333091
Ulcerative colitis (UC) is an idiopathic chronic inflammatory disease of the colon with sharply rising global prevalence. Dysfunctional epithelial compartment (EC) dynamics are implicated in UC pathogenesis although EC-specific studies...
7.
Livanos A, Dunn A, Fischer J, Ungaro R, Turpin W, Lee S, et al.
Gastroenterology . 2023 Jan; 164(4):619-629. PMID: 36634824
Background & Aims: Better biomarkers for prediction of ulcerative colitis (UC) development and prognostication are needed. Anti-integrin αvβ6 (anti-αvβ6) autoantibodies have been described in patients with UC. We tested for...
8.
Uzzan M, Martin J, Mesin L, Livanos A, Castro-Dopico T, Huang R, et al.
Nat Med . 2022 Feb; 28(4):766-779. PMID: 35190725
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n = 145;...
9.
Britton G, Chen-Liaw A, Cossarini F, Livanos A, Spindler M, Plitt T, et al.
Sci Rep . 2021 Jun; 11(1):13308. PMID: 34172783
Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from...
10.
Livanos A, Jha D, Cossarini F, Gonzalez-Reiche A, Tokuyama M, Aydillo T, et al.
Gastroenterology . 2021 Mar; 160(7):2435-2450.e34. PMID: 33676971
Background & Aims: Given that gastrointestinal (GI) symptoms are a prominent extrapulmonary manifestation of COVID-19, we investigated intestinal infection with SARS-CoV-2, its effect on pathogenesis, and clinical significance. Methods: Human...