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Andrea Cerutti

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Articles 116
Citations 6713
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Recent Articles
1.
Gutzeit C, Grasset E, Matthews D, Maglione P, Britton G, Miller H, et al.
Sci Adv . 2025 Feb; 11(7):eado9455. PMID: 39937896
The gut microbiota enhances systemic immunoglobulin G (IgG) responses to vaccines, but it is unknown whether this effect involves IgA, which coats intestinal microbes. That IgA may amplify postimmune IgG...
2.
Tejedor Vaquero S, Neuman H, Comerma L, Marcos-Fa X, Corral-Vazquez C, Uzzan M, et al.
J Exp Med . 2024 Nov; 221(12). PMID: 39560666
The human gut includes plasma cells (PCs) expressing immunoglobulin A1 (IgA1) or IgA2, two structurally distinct IgA subclasses with elusive regulation, function, and reactivity. We show here that intestinal IgA1+...
3.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
Sci Immunol . 2024 Oct; 9(100):eado0090. PMID: 39454027
Gastrointestinal (GI) B cells and plasma cells (PCs) are critical to mucosal homeostasis and the host response to HIV-1 infection. Here, high-resolution mapping of human B cells and PCs sampled...
4.
Claria J, Aguilar F, Lozano J, Jimenez-Gracia L, Nieto J, Romero-Grimaldo B, et al.
JHEP Rep . 2024 Oct; 6(11):101184. PMID: 39434891
Background & Aims: Patients with acutely decompensated (AD) cirrhosis are immunocompromised and particularly susceptible to infections. This study investigated the immunomodulatory actions of albumin by which this protein may lower...
5.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
bioRxiv . 2024 Jun; PMID: 38826293
One Sentence Summary: Intestinal germinal center B cell reduction in HIV-1 infection linked to reduced IgA plasma cells and systemic inflammation.
6.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski R, Verstockt B, Livanos A, et al.
Sci Immunol . 2024 Apr; 9(94):eadg7549. PMID: 38640252
Vedolizumab (VDZ) is a first-line treatment in ulcerative colitis (UC) that targets the α4β7- mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) axis. To determine the mechanisms of action of...
7.
Zhou J, Huang B, Pei B, Sun G, Pawlitz M, Zhang W, et al.
bioRxiv . 2024 Jan; PMID: 38260362
In response to antigens, B cells undergo affinity maturation and class switching mediated by activation-induced cytidine deaminase (AID) in germinal centers (GCs) of secondary lymphoid organs, but uncontrolled AID activity...
8.
Canales-Herrerias P, Cerutti A
Cell Host Microbe . 2023 Oct; 31(10):1595-1597. PMID: 37827118
In this issue of Cell Host & Microbe, Zhang et al. show that long-term oral administration of a pectin-derived prebiotic broadly enhanced IgA responses to commensals in the small intestine....
9.
Mascaro J, Rodriguez-Pinto I, Poza G, Mensa-Vilaro A, Fernandez-Martin J, Caminal-Montero L, et al.
Ann Rheum Dis . 2023 Sep; 82(12):1594-1605. PMID: 37666646
Background: The vacuoles, E1-enzyme, X linked, autoinflammatory and somatic (VEXAS) syndrome is an adult-onset autoinflammatory disease (AID) due to postzygotic variants. Objectives: To investigate the presence of VEXAS syndrome among...
10.
Garcia-Carmona Y, Fribourg M, Sowa A, Cerutti A, Cunningham-Rundles C
Clin Immunol . 2023 Jul; 253:109689. PMID: 37422057
While many of the genes and molecular pathways in the germinal center B cell response which initiate protective antibody production are known, the contributions of individual molecular players in terminal...