Divya Jha
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Explore the profile of Divya Jha including associated specialties, affiliations and a list of published articles.
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19
Citations
1658
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Recent Articles
1.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
Sci Immunol
. 2024 Oct;
9(100):eado0090.
PMID: 39454027
Gastrointestinal (GI) B cells and plasma cells (PCs) are critical to mucosal homeostasis and the host response to HIV-1 infection. Here, high-resolution mapping of human B cells and PCs sampled...
2.
Cossarini F, Shang J, Krek A, Al-Taie Z, Hou R, Canales-Herrerias P, et al.
bioRxiv
. 2024 Jun;
PMID: 38826293
One Sentence Summary: Intestinal germinal center B cell reduction in HIV-1 infection linked to reduced IgA plasma cells and systemic inflammation.
3.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski R, Verstockt B, Livanos A, et al.
Sci Immunol
. 2024 Apr;
9(94):eadg7549.
PMID: 38640252
Vedolizumab (VDZ) is a first-line treatment in ulcerative colitis (UC) that targets the α4β7- mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) axis. To determine the mechanisms of action of...
4.
Li X, La Salvia S, Liang Y, Adamiak M, Kohlbrenner E, Jeong D, et al.
Circulation
. 2023 Jul;
148(5):405-425.
PMID: 37409482
Background: Adeno-associated virus (AAV) has emerged as one of the best tools for cardiac gene delivery due to its cardiotropism, long-term expression, and safety. However, a significant challenge to its...
5.
Jha D, Al-Taie Z, Krek A, Toghi Eshghi S, Fantou A, Laurent T, et al.
bioRxiv
. 2023 Jun;
PMID: 37333091
Ulcerative colitis (UC) is an idiopathic chronic inflammatory disease of the colon with sharply rising global prevalence. Dysfunctional epithelial compartment (EC) dynamics are implicated in UC pathogenesis although EC-specific studies...
6.
Canales-Herrerias P, Uzzan M, Seki A, Czepielewski R, Verstockt B, Livanos A, et al.
bioRxiv
. 2023 Jan;
PMID: 36711839
Targeting the α4β7-MAdCAM-1 axis with vedolizumab (VDZ) is a front-line therapeutic paradigm in ulcerative colitis (UC). However, mechanism(s) of action (MOA) of VDZ remain relatively undefined. Here, we examined three...
7.
Uzzan M, Martin J, Mesin L, Livanos A, Castro-Dopico T, Huang R, et al.
Nat Med
. 2022 Feb;
28(4):766-779.
PMID: 35190725
B cells, which are critical for intestinal homeostasis, remain understudied in ulcerative colitis (UC). In this study, we recruited three cohorts of patients with UC (primary cohort, n = 145;...
8.
Britton G, Chen-Liaw A, Cossarini F, Livanos A, Spindler M, Plitt T, et al.
Sci Rep
. 2021 Jun;
11(1):13308.
PMID: 34172783
Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from...
9.
Livanos A, Jha D, Cossarini F, Gonzalez-Reiche A, Tokuyama M, Aydillo T, et al.
Gastroenterology
. 2021 Mar;
160(7):2435-2450.e34.
PMID: 33676971
Background & Aims: Given that gastrointestinal (GI) symptoms are a prominent extrapulmonary manifestation of COVID-19, we investigated intestinal infection with SARS-CoV-2, its effect on pathogenesis, and clinical significance. Methods: Human...
10.
Gaebler C, Wang Z, Lorenzi J, Muecksch F, Finkin S, Tokuyama M, et al.
Nature
. 2021 Jan;
591(7851):639-644.
PMID: 33461210
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million individuals and is responsible for over 1.7 million deaths to date. Infection is associated with the development of variable...