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Alexander Y Andreyev

Explore the profile of Alexander Y Andreyev including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 837
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Recent Articles
11.
Wiley S, Andreyev A, Divakaruni A, Karisch R, Perkins G, Wall E, et al.
EMBO Mol Med . 2013 May; 5(6):904-18. PMID: 23703906
Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan. Embryonic fibroblasts from Miner1(-/-)...
12.
Divakaruni A, Wiley S, Rogers G, Andreyev A, Petrosyan S, Loviscach M, et al.
Proc Natl Acad Sci U S A . 2013 Mar; 110(14):5422-7. PMID: 23513224
Facilitated pyruvate transport across the mitochondrial inner membrane is a critical step in carbohydrate, amino acid, and lipid metabolism. We report that clinically relevant concentrations of thiazolidinediones (TZDs), a widely...
13.
Kushnareva Y, Andreyev A, Kuwana T, Newmeyer D
PLoS Biol . 2012 Oct; 10(9):e1001394. PMID: 23049480
Bax/Bak-mediated mitochondrial outer membrane permeabilization (MOMP) is essential for "intrinsic" apoptotic cell death. Published studies used synthetic liposomes to reveal an intrinsic pore-forming activity of Bax, but it is unclear...
14.
Andreyev A, Fahy E, Guan Z, Kelly S, Li X, McDonald J, et al.
J Lipid Res . 2010 Jun; 51(9):2785-97. PMID: 20574076
Lipids orchestrate biological processes by acting remotely as signaling molecules or locally as membrane components that modulate protein function. Detailed insight into lipid function requires knowledge of the subcellular localization...
15.
Andreyev A, Shen Z, Guan Z, Ryan A, Fahy E, Subramaniam S, et al.
Mol Cell Proteomics . 2009 Nov; 9(2):388-402. PMID: 19884172
Compartmentalization of biological processes and the associated cellular components is crucial for cell function. Typically, the location of a component is revealed through a co-localization and/or co-purification with an organelle...
16.
Lee J, Kim C, Simon D, Aminova L, Andreyev A, Kushnareva Y, et al.
J Biol Chem . 2005 Oct; 280(49):40398-401. PMID: 16207717
Cyclic AMP response element-binding protein (CREB) is a widely expressed transcription factor whose role in neuronal protection is now well established. Here we report that CREB is present in the...
17.
Kushnareva Y, Wiley S, Ward M, Andreyev A, Murphy A
J Biol Chem . 2005 Jun; 280(32):28894-902. PMID: 15932874
Neuronal death in response to excitotoxic levels of glutamate is dependent upon mitochondrial Ca2+ accumulation and is associated with a drop in ATP levels and a loss in ionic homeostasis....