Alexander Y Andreyev
Overview
Explore the profile of Alexander Y Andreyev including associated specialties, affiliations and a list of published articles.
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17
Citations
837
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Recent Articles
1.
Andreyev A, Yang H, Doulias P, Dolatabadi N, Zhang X, Luevanos M, et al.
Adv Sci (Weinh)
. 2024 Jan;
11(12):e2306469.
PMID: 38235614
In Alzheimer's disease (AD), dysfunctional mitochondrial metabolism is associated with synaptic loss, the major pathological correlate of cognitive decline. Mechanistic insight for this relationship, however, is still lacking. Here, comparing...
2.
Doulias P, Yang H, Andreyev A, Dolatabadi N, Scott H, K Raspur C, et al.
Cell Chem Biol
. 2023 Jul;
30(8):965-975.e6.
PMID: 37478858
A causal relationship between mitochondrial metabolic dysfunction and neurodegeneration has been implicated in synucleinopathies, including Parkinson disease (PD) and Lewy body dementia (LBD), but underlying mechanisms are not fully understood....
3.
Tillo M, Lamanna W, Dwyer C, Sandoval D, Pessentheiner A, Al-Azzam N, et al.
J Biol Chem
. 2022 Jun;
298(8):102159.
PMID: 35750212
Lysosomal storage diseases result in various developmental and physiological complications, including cachexia. To study the causes for the negative energy balance associated with cachexia, we assessed the impact of sulfamidase...
4.
Zhao M, Quintana A, Zhang C, Andreyev A, Kiosses W, Kuwana T, et al.
EMBO J
. 2021 Jun;
40(16):e107901.
PMID: 34169542
How natural or innate-like lymphocytes generate the capacity to produce IL-4 and other cytokines characteristic of type 2 immunity remains unknown. Invariant natural killer T (iNKT) cells differentiate in the...
5.
Riffelmacher T, Giles D, Zahner S, Dicker M, Andreyev A, McArdle S, et al.
Mucosal Immunol
. 2021 Feb;
14(3):679-690.
PMID: 33568785
Inflammatory bowel disease is characterized by an exacerbated intestinal immune response, but the critical mechanisms regulating immune activation remain incompletely understood. We previously reported that the TNF-superfamily molecule TNFSF14 (LIGHT)...
6.
Kushnareva Y, Mathews I, Andreyev A, Altay G, Arlehamn C, Pandurangan V, et al.
J Immunol
. 2021 Feb;
206(6):1181-1193.
PMID: 33547171
CCR6CXCR3CCR4CD4 memory T cells, termed Th1*, are important for long-term immunity to and the pathogenesis of autoimmune diseases. Th1* cells express a unique set of lineage-specific transcription factors characteristic of...
7.
Divakaruni A, Hsieh W, Minarrieta L, Duong T, Kim K, Desousa B, et al.
Cell Metab
. 2018 Jul;
28(3):490-503.e7.
PMID: 30043752
Long-chain fatty acid (LCFA) oxidation has been shown to play an important role in interleukin-4 (IL-4)-mediated macrophage polarization (M(IL-4)). However, many of these conclusions are based on the inhibition of...
8.
Divakaruni A, Andreyev A, Rogers G, Murphy A
Anal Biochem
. 2017 Oct;
552:60-65.
PMID: 28987935
Activities of enzymes localized to the mitochondrial matrix of mammalian cells are often critical regulatory steps in cellular metabolism. As such, measurement of matrix enzyme activities in response to genetic...
9.
Divakaruni A, Wallace M, Buren C, Martyniuk K, Andreyev A, Li E, et al.
J Cell Biol
. 2017 Mar;
216(4):1091-1105.
PMID: 28254829
Glutamate is the dominant excitatory neurotransmitter in the brain, but under conditions of metabolic stress it can accumulate to excitotoxic levels. Although pharmacologic modulation of excitatory amino acid receptors is...
10.
Andreyev A, Tsui H, Milne G, Shmanai V, Bekish A, Fomich M, et al.
Free Radic Biol Med
. 2015 Jan;
82:63-72.
PMID: 25578654
Polyunsaturated fatty acid (PUFA) peroxidation is initiated by hydrogen atom abstraction at bis-allylic sites and sets in motion a chain reaction that generates multiple toxic products associated with numerous disorders....