Alexander W Charney
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Explore the profile of Alexander W Charney including associated specialties, affiliations and a list of published articles.
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99
Citations
5522
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Recent Articles
1.
Wang C, Wang S, Xue Y, Zhong Y, Li H, Hou X, et al.
Nat Biotechnol
. 2025 Mar;
PMID: 40038437
No abstract available.
2.
Wang C, Xue Y, Markovic T, Li H, Wang S, Zhong Y, et al.
Nat Mater
. 2025 Feb;
PMID: 39962245
The systemic delivery of mRNA molecules to the central nervous system is challenging as they need to cross the blood-brain barrier (BBB) to reach into the brain. Here we design...
3.
Jayaraman P, Rajagopal M, Paranjpe I, Suarez-Farinas M, Liharska L, Thompson R, et al.
Kidney360
. 2025 Feb;
PMID: 39899385
Background: Acute kidney injury (AKI) is common in SARS-CoV-2 infection and COVID-19, often leading to long-term kidney dysfunction. However, the transcriptomic features of AKI severity and its long-term effects are...
4.
Shah D, Thaweethai T, Karlson E, Bonilla H, Horne B, Mullington J, et al.
JAMA Netw Open
. 2025 Jan;
8(1):e2455430.
PMID: 39841477
Importance: A substantial number of individuals worldwide experience long COVID, or post-COVID condition. Other postviral and autoimmune conditions have a female predominance, but whether the same is true for long...
5.
Jangda M, Patel J, Gill J, McCarthy P, Desman J, Gupta R, et al.
medRxiv
. 2025 Jan;
PMID: 39830234
Achieving adequate enteral nutrition among mechanically ventilated patients is challenging, yet critical. We developed NutriSighT, a transformer model using learnable positional coding to predict which patients would achieve hypocaloric nutrition...
6.
Lepow L, Adekkanattu P, Cusick M, Coon H, Fennessy B, OConnell S, et al.
medRxiv
. 2025 Jan;
PMID: 39763535
Importance: Diagnostic codes in the Electronic Health Record (EHR) are known to be limited in reporting patient suicidality, and especially in differentiating the levels of suicide severity. Objective: The authors...
7.
Xu J, Liu D, Hassan A, Genovese G, Cote A, Fennessy B, et al.
HGG Adv
. 2024 Dec;
6(2):100395.
PMID: 39696820
Genotype imputation is crucial for genome-wide association studies (GWASs), but reference panels and existing benchmarking studies prioritize European individuals. Consequently, it is unclear which publicly available reference panel should be...
8.
Soffer S, Nesselroth D, Pragier K, Anteby R, Apakama D, Holmes E, et al.
Res Sq
. 2024 Nov;
PMID: 39606472
Importance: Medical ethics is inherently complex, shaped by a broad spectrum of opinions, experiences, and cultural perspectives. The integration of large language models (LLMs) in healthcare is new and requires...
9.
Simmons A, Takkavatakarn K, McDougal M, Dilcher B, Pincavitch J, Meadows L, et al.
medRxiv
. 2024 Nov;
PMID: 39606395
Background: Healthcare reimbursement and coding is dependent on accurate extraction of International Classification of Diseases-tenth revision - clinical modification (ICD-10-CM) codes from clinical documentation. Attempts to automate this task have...
10.
Wang C, Wang S, Xue Y, Zhong Y, Li H, Hou X, et al.
Nat Biotechnol
. 2024 Nov;
PMID: 39587229
Delivery of biomacromolecules to the central nervous system (CNS) remains challenging because of the restrictive nature of the blood-brain barrier (BBB). We developed a BBB-crossing conjugate (BCC) system that facilitates...