Alexander W Charney
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Explore the profile of Alexander W Charney including associated specialties, affiliations and a list of published articles.
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99
Citations
5522
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Recent Articles
11.
Klang E, Apakama D, Abbott E, Vaid A, Lampert J, Sakhuja A, et al.
NPJ Digit Med
. 2024 Nov;
7(1):320.
PMID: 39558090
Large language models (LLMs) can optimize clinical workflows; however, the economic and computational challenges of their utilization at the health system scale are underexplored. We evaluated how concatenating queries with...
12.
Klang E, Tessler I, Apakama D, Abbott E, Glicksberg B, Arnold M, et al.
medRxiv
. 2024 Nov;
PMID: 39484238
Background: Accurate medical coding is essential for clinical and administrative purposes but complicated, time-consuming, and biased. This study compares Retrieval-Augmented Generation (RAG)-enhanced LLMs to provider-assigned codes in producing ICD-10-CM codes...
13.
Gopal Patra B, Lepow L, Kasi Reddy Jagadeesh Kumar P, Vekaria V, Sharma M, Adekkanattu P, et al.
J Am Med Inform Assoc
. 2024 Oct;
32(1):218-226.
PMID: 39423850
Objectives: Social support (SS) and social isolation (SI) are social determinants of health (SDOH) associated with psychiatric outcomes. In electronic health records (EHRs), individual-level SS/SI is typically documented in narrative...
14.
Coombes B, Sanchez-Ruiz J, Fennessy B, Pazdernik V, Adekkanattu P, Nunez N, et al.
Psychiatry Res
. 2024 Sep;
342():116203.
PMID: 39321638
Treatment resistance is common in major depressive disorder (MDD), yet clinical risk factors are not well understood. Using a discovery-replication design, we conducted phenome-wide association studies (PheWASs) of MDD treatment...
15.
Gulamali F, Jayaraman P, Sawant A, Desman J, Fox B, Chang A, et al.
NPJ Digit Med
. 2024 Sep;
7(1):233.
PMID: 39237755
Increased intracranial pressure (ICP) ≥15 mmHg is associated with adverse neurological outcomes, but needs invasive intracranial monitoring. Using the publicly available MIMIC-III Waveform Database (2000-2013) from Boston, we developed an...
16.
Oh W, Takkavatakarn K, Kittrell H, Shawwa K, Gomez H, Sawant A, et al.
medRxiv
. 2024 Aug;
PMID: 39148835
Rationale: Intravenous fluids are mainstay of management of acute kidney injury (AKI) after sepsis but can cause fluid overload. Recent literature shows that restrictive fluid strategy may be beneficial in...
17.
Erlandson K, Geng L, Selvaggi C, Thaweethai T, Chen P, Erdmann N, et al.
Ann Intern Med
. 2024 Aug;
177(9):1209-1221.
PMID: 39133923
Background: There are currently no validated clinical biomarkers of postacute sequelae of SARS-CoV-2 infection (PASC). Objective: To investigate clinical laboratory markers of SARS-CoV-2 and PASC. Design: Propensity score-weighted linear regression...
18.
de Los Santos M, Kopell B, Buxbaum Grice A, Ganesh G, Yang A, Amini P, et al.
Nat Commun
. 2024 Jul;
15(1):5828.
PMID: 38992062
No abstract available.
19.
Omar M, Soffer S, Charney A, Landi I, Nadkarni G, Klang E
Front Psychiatry
. 2024 Jul;
15:1422807.
PMID: 38979501
Background: With their unmatched ability to interpret and engage with human language and context, large language models (LLMs) hint at the potential to bridge AI and human cognitive processes. This...
20.
de Los Santos M, Kopell B, Buxbaum Grice A, Ganesh G, Yang A, Amini P, et al.
Nat Commun
. 2024 Jun;
15(1):5366.
PMID: 38926387
Adenosine-to-inosine (A-to-I) editing is a prevalent post-transcriptional RNA modification within the brain. Yet, most research has relied on postmortem samples, assuming it is an accurate representation of RNA biology in...